التفاصيل البيبلوغرافية
| العنوان: |
A Method for the Immobilization of Chitosan onto Urinary Catheters. |
| المؤلفون: |
Vesel, Alenka, Recek, Nina, Zaplotnik, Rok, Kurinčič, Albert, Kuzmič, Katja, Zemljič, Lidija Fras |
| المصدر: |
International Journal of Molecular Sciences; Dec2022, Vol. 23 Issue 23, p15075, 18p |
| مصطلحات موضوعية: |
URINARY catheters, OXYGEN plasmas, THERAPEUTIC immobilization, CHITOSAN, X-ray photoelectron spectroscopy, INFRARED spectroscopy |
| مستخلص: |
A method for the immobilization of an antibacterial chitosan coating to polymeric urinary medical catheters is presented. The method comprises a two-step plasma-treatment procedure, followed by the deposition of chitosan from the water solution. In the first plasma step, the urinary catheter is treated with vacuum-ultraviolet radiation to break bonds in the polymer surface film and create dangling bonds, which are occupied by hydrogen atoms. In the second plasma step, polymeric catheters are treated with atomic oxygen to form oxygen-containing surface functional groups acting as binding sites for chitosan. The presence of oxygen functional groups also causes a transformation of the hydrophobic polymer surface to hydrophilic, thus enabling uniform wetting and improved adsorption of the chitosan coating. The wettability was measured by the sessile-drop method, while the surface composition and structure were measured by X-ray photoelectron spectroscopy and Fourier-transform infrared spectroscopy. Non-treated samples did not exhibit successful chitosan immobilization. The effect of plasma treatment on immobilization was explained by noncovalent interactions such as electrostatic interactions and hydrogen bonds. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
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