التفاصيل البيبلوغرافية
| العنوان: |
Race and ethnicity representation in clinical trials: findings from a literature review of Phase I oncology trials. |
| المؤلفون: |
Camidge, D Ross, Park, Haeseong, Smoyer, Karen E, Jacobs, Ira, Lee, Lauren J, Askerova, Zemfira, McGinnis, Justin, Zakharia, Yousef |
| المصدر: |
Future Oncology; Aug2021, Vol. 17 Issue 24, p3271-3280, 10p |
| مستخلص: |
Aim: To provide an assessment of published literature on the demographic representation in Phase I trials of biopharmaceutical oncology agents. Materials & methods: We conducted a rapid evidence assessment to identify demographic representation reported in Phase I clinical trials for biopharmaceutical oncology agents published in 2019. Results: Globally, the population was predominantly White/Caucasian (62.2%). In the USA, the distribution was heavily skewed toward White/Caucasian (84.2%), with minimal representation of Blacks/African-Americans (7.3%), Asians (3.4%), Hispanics/Latinos (2.8%) or other race/ethnicity groups. Conclusion: Our data highlight that Phase I oncology trials do not reflect the population at large, which may perpetuate health disparities. Further research is needed to understand and address barriers to participation, particularly among under-represented groups. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
