دورية أكاديمية

Clinical impact of BRCA2 mRNA expression in high-grade serous ovarian cancer: validation using the TCGA cohort.

التفاصيل البيبلوغرافية
العنوان: Clinical impact of BRCA2 mRNA expression in high-grade serous ovarian cancer: validation using the TCGA cohort.
المؤلفون: Tsibulak, Irina, Wieser, Verena, Welponer, Hannah, Leitner, Katharina, Hackl, Hubert, Marth, Christian, Fiegl, Heidelinde, Zeimet, Alain G.
المصدر: Acta Oncologica; Feb2021, Vol. 60 Issue 2, p187-190, 4p, 1 Chart, 1 Graph
مصطلحات موضوعية: GENE expression, MESSENGER RNA, GENETIC mutation, NONPARAMETRIC statistics, OVARIAN tumors, STATISTICS, SURVIVAL analysis (Biometry), BRCA genes, DATA analysis software, GENE expression profiling, DESCRIPTIVE statistics, KAPLAN-Meier estimator, MANN Whitney U Test, TUMOR grading
مستخلص: In the article, the authors present their study on the clinical effects of breast cancer 2 messenger ribonucleic acid (BRCA2 mRNA) expression in high-grade serous ovarian cancer (HGSOC) using dataset from The Cancer Genome Atlas (TCGA) project. Topics include the percentage of epithelial OCs that are hereditary, and the use of tests like the non-parametric Mann-Whitney U test and univariate Kaplan-Meier analyses in the study.
قاعدة البيانات: Complementary Index
الوصف
تدمد:0284186X
DOI:10.1080/0284186X.2020.1841288