التفاصيل البيبلوغرافية
| العنوان: |
Lyciyunin, a new dimer of feruloyltyramine and five bioactive tyramines from the root of Lycium yunnanense Kuang. |
| المؤلفون: |
Xia, Zhao, Xu, Tian-qi, Xu, Wei, Zhang, Hai-xin, Liang, Qiu-ping, Zhou, Guang-xiong |
| المصدر: |
Natural Product Research; Feb2021, Vol. 35 Issue 3, p447-454, 8p |
| مصطلحات موضوعية: |
ANTIOXIDANT testing, QUANTUM chemistry, MACROPHAGES |
| مستخلص: |
Lyciyunin, a new dimer of feruloyltyramine (1), together with five known tyramines (2–6), was isolated from the water-soluble fraction of an EtOH extract of the root of L. yunnanense. Based on HR-TOF-MS, NMR spectral data and quantum chemistry ECD calculations, the structure of this new compound was determined, including its absolute configuration. Compounds (1–6) were tested for their antioxidant activity using in vitro DPPH radical scavenging assay, and 1–6 showed the moderate antioxidant activities with IC50 values of 12.44 ± 0.39, 21.29 ± 0.75, 24.44 ± 1.63, 21.15 ± 0.66, 21.15 ± 0.66 and 45.15 ± 0.56 μM, respectively. Compounds (5–6) showed anti-inflammatory activity in LPS-induced RAW 264.7 macrophages with the IC50 values of 43.95 ± 6.11 and 33.50 ± 2.04 μM, respectively. [ABSTRACT FROM AUTHOR] |
|
Copyright of Natural Product Research is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
