التفاصيل البيبلوغرافية
| العنوان: |
Interleukin-6 Receptor (IL-6R) Expression in Human Gastric Carcinoma and its Clinical Significance. |
| المؤلفون: |
Simondurairaj, C., Krishnakumar, R., Sundaram, Sandhya, Venkatraman, Ganesh |
| المصدر: |
Cancer Investigation; 2019, Vol. 37 Issue 7, p293-298, 6p |
| مصطلحات موضوعية: |
CANCER patients, CELL lines, CELL receptors, CYTOKINES, GENE expression, IMMUNOHISTOCHEMISTRY, INTERLEUKINS, STAINS & staining (Microscopy), STOMACH tumors, BLOOD |
| مستخلص: |
The aim of the study is to analyse the expression of Interleukin-6 receptor in different human gastric tissue and to correlate with the clinicopathological features of the patients. Immunohistochemistry was done against the IL-6R antibody and the Q-score was calculated from the staining pattern. Higher Q-scores were observed in tumour cells than the adjacent normal cells which were statistically significant. We also observed a significant correlation between the expressions of IL-6R and the clinicopathological features These findings suggest that IL-6R may represent as a therapeutic target for gastric carcinoma and serve as a prognostic indicator, as well. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
