التفاصيل البيبلوغرافية
| العنوان: |
Efficacy of an Education Program for People With Diabetes and Insulin Pump Treatment (INPUT): Results From a Randomized Controlled Trial. |
| المؤلفون: |
Ehrmann, Dominic, Kulzer, Bernhard, Schipfer, Melanie, Lippmann-Grob, Bernhard, Haak, Thomas, Hermanns, Norbert |
| المصدر: |
Diabetes Care; 2018, Vol. 41 Issue 12, p2453-2462, 10p |
| مصطلحات موضوعية: |
TREATMENT of diabetes, INSULIN therapy, INSULIN pumps, HYPOGLYCEMIA, RANDOMIZED controlled trials, BLOOD sugar, COMPARATIVE studies, DIABETES, HYPOGLYCEMIC agents, INSULIN, RESEARCH methodology, MEDICAL cooperation, PATIENT education, RESEARCH, STATISTICAL sampling, EVALUATION research, TREATMENT effectiveness |
| مستخلص: |
Objective: Continuous subcutaneous insulin infusion (CSII) is the most advanced form of insulin delivery, but it requires structured education to provide users with the necessary knowledge/skills and to support their motivation. Currently, no structured education program designed to provide this training has been evaluated. We developed a CSII-specific, structured education program (Insulin Pump Treatment [INPUT]) and evaluated its impact on glycemic control, behavior, and psychosocial status.Research Design and Methods: This was a multicenter, randomized, parallel trial with a 6-month follow-up. Eligible participants (age 16-75 years) currently were treated with insulin pump therapy. Participants were randomly assigned (1:1) to the INPUT program or to usual care using a computer-generated algorithm, with study center as the stratification factor. The primary outcome was HbA1c change from baseline to 6 months. Secondary outcomes were incidence of severe hypoglycemia and changes in behavioral and psychosocial measures.Results: Between 1 April 2016 and 26 April 2016, 268 people with diabetes and a mean duration of CSII therapy of 9.5 years were randomly assigned to the INPUT group (n = 135) or control group (n = 133). At 6 months, HbA1c improved in the INPUT group (8.33 ± 0.8 vs. 8.04 ± 0.9; P < 0.0001) but not in the control group (8.33 ± 1.0 vs. 8.27 ± 1.0; P = 0.11). The between-group difference in HbA1c reduction was significant, favoring INPUT (-0.28% vs. -0.06%, Δ -0.22%, 95% CI -0.38 to -0.06; P = 0.0029). The incidence rate ratio of severe hypoglycemia was 3.55 times higher for participants in the control group than for those in the INPUT group (95% CI 1.50-8.43; P = 0.0041).Conclusions: The INPUT education program led to a significant improvement in glycemic control and incidence of severe hypoglycemia in insulin pump users. [ABSTRACT FROM AUTHOR] |
|
Copyright of Diabetes Care is the property of American Diabetes Association and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder