التفاصيل البيبلوغرافية
| العنوان: |
Sludge reflects intra‐amniotic inflammation with or without microorganisms. |
| المؤلفون: |
Yoneda, Noriko, Yoneda, Satoshi, Niimi, Hideki, Ito, Masami, Fukuta, Kaori, Ueno, Tomohiro, Ito, Mika, Shiozaki, Arihiro, Kigawa, Mika, Kitajima, Isao, Saito, Shigeru |
| المصدر: |
American Journal of Reproductive Immunology; Feb2018, Vol. 79 Issue 2, p1-1, 8p |
| مصطلحات موضوعية: |
AMNIOTIC liquid, PREMATURE labor, PREGNANCY complications, TRANSVAGINAL ultrasonography, INFLAMMATION, POLYMERASE chain reaction |
| مستخلص: |
Problem: To investigate whether amniotic fluid (AF) “sludge” in patients with preterm labor (PTL) with intact membranes is related to intra‐amniotic infection or inflammation. Method of study: 105 PTL patients before 29 weeks’ gestation were enrolled. AF “sludge” was evaluated by transvaginal sonography. Microorganisms were identified in AF by our newly established PCR method using a eukaryote‐made thermostable DNA polymerase. Results: AF “sludge” was present in 18.1% (19/105) of patients. The results obtained in the AF “sludge” group vs the no “sludge” group were as follows: (i) a similar positive rate of microorganisms in AF by PCR, 31.6% (6/19) vs 38.4% (33/86); (ii) a higher level of AF interleukin‐8, 15.2 (0.2‐381.5) ng/mL vs 5.8 (0.1‐413.7) ng/mL; P = .005); and (3) a higher frequency of histological chorioamnionitis, 52.6% (10/19) vs 23.3% (20/86); P = .010. Conclusion: The presence of AF “sludge” is related to intra‐amniotic inflammation with or without microorganisms. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
