التفاصيل البيبلوغرافية
| العنوان: |
Parkinson's Impulse-Control Scale for the Severity Rating of Impulse-Control Behaviors in Parkinson's Disease: A Semistructured Clinical Assessment Tool. |
| المؤلفون: |
Okai, David, Askey‐Jones, Sally, Mack, Joel, Martin, Anne, Chaudhuri, Kallol Ray, Samuel, Michael, David, Anthony S., Brown, Richard G. |
| المصدر: |
Movement Disorders Clinical Practice; Sep/Oct2016, Vol. 3 Issue 5, p494-499, 6p |
| مصطلحات موضوعية: |
IMPULSE control disorders, PARKINSON'S disease, SEVERITY of illness index, COMPULSIVE gambling, COMPULSIVE shopping, COMPULSIVE eating, BEHAVIOR therapy, RANDOMIZED controlled trials, THERAPEUTICS |
| مستخلص: |
Background Impulse-control behaviors ( ICBs) are increasingly recognized in Parkinson's disease ( PD) as drug-related effects of dopaminergic mediation that occur in 15% to 35% of patients with PD. The authors describe the design and evaluation of a new, clinician-rated severity scale for the assessment of syndromal and subsyndromal forms of impulse-control disorders ( ICDs), simple (punding) and complex (hobbyism) repetitive behaviors, and compulsive overuse of medication (dopamine dysregulation syndrome). Methods The Parkinson's Impulse-Control Scale ( PICS), the first PD-specific, semistructured interview to cover the full range of PD-related ICBs, is described along with initial evidence on its clinimetric properties including interrater reliability, discriminant validity and sensitivity to change. A convenience sample of PD patients with ICBs and those without were administered a semistructured interview (n = 92). Results The scale distinguished between those with and without clinically detected ICBs and between patients with syndromal ICD and subsyndromal ICB (receiver operating characteristic areas under the curve, 92%-95%). Cutoff values were suggested, and substantial agreement was reported on weighted kappa (Κ) values for clinician-clinician rating of severity (Κ = 0.92). Significant improvements were detected on the scale after a randomized controlled trial of cognitive-behavioral therapy and medication adjustment ( t[22] = 5.47; P < 0.001). Conclusions The PICS appears to be a reliable measure of the full range of PD ICBs with good levels of interrater reliability. It may provide a useful measure to assess the severity of ICBs and monitor change in clinical and research settings; although, given the specialized centers used for recruitment of this sample, further psychometric evaluation is required. [ABSTRACT FROM AUTHOR] |
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