دورية أكاديمية

Necrotizing herpetic retinopathy in an immune-compromised pediatric patient with minimal signs of inflammation: case report.

التفاصيل البيبلوغرافية
العنوان: Necrotizing herpetic retinopathy in an immune-compromised pediatric patient with minimal signs of inflammation: case report.
المؤلفون: Soon Il Choi, Jae Ryun Kim, Ho Ra, Choi, Soon Il, Kim, Jae Ryun, Ra, Ho
المصدر: BMC Ophthalmology; 6/8/2016, Vol. 16, p1-5, 5p
مصطلحات موضوعية: ANTI-inflammatory agents, RETROLENTAL fibroplasia, CHILDREN'S health, HOSPITAL care of children, PEDIATRIC ophthalmology
مستخلص: Background: To report a case of necrotizing herpetic retinopathy(NHR) in an immuno-compromised pediatric patient.Case Presentation: An 11-year-old boy presented with a minimal ocular foreign-body sensation and peripheral visual-field defect, as well as mild upper respiratory symptoms. He had undergone the Fontan operation for a ventricular septal defect and single ventricle during infancy, and had been taking oral steroids for 1 year immediately prior to his presentation to treat protein-losing enteropathy. Initially, a case of either cytomegalovirus (CMV) retinitis or acute retinal necrosis (ARN) was suspected, and an intravenous course of ganciclovir and acyclovir was therefore initiated. During treatment, varicella-zoster virus (VZV) was detected in the anterior chamber, and ARN was confirmed when both serum and aqueous humor were found by polymerase chain reaction (PCR) to be positive for VZV DNA. A peripheral retinal break and detachment developed after medical treatment, and a vitrectomy was performed.Conclusions: Typically, ARN is found in both healthy individuals and subclinically immuno-compromised patients of any age. CMV retinitis is somewhat more typical for immuno-compromised patients. Herein, we report a case of NHR in a pediatric patient with poor general condition and showing minimal signs of inflammation. [ABSTRACT FROM AUTHOR]
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قاعدة البيانات: Complementary Index
الوصف
تدمد:14712415
DOI:10.1186/s12886-016-0253-x