التفاصيل البيبلوغرافية
| العنوان: |
Prenatal Diagnosis and Postnatal Outcome of Schizencephaly. |
| المؤلفون: |
Kutuk, Mehmet Serdar, Gorkem, Sureyya Burcu, Bayram, Ayse, Doganay, Selim, Canpolat, Mehmet, Basbug, Mustafa |
| المصدر: |
Journal of Child Neurology; Sep2015, Vol. 30 Issue 10, p1388-1394, 7p |
| مصطلحات موضوعية: |
PRENATAL diagnosis, MAGNETIC resonance imaging, ULTRASONIC imaging, HYDROCEPHALUS, LISSENCEPHALY |
| مستخلص: |
The aim of this study was to present our experience with 5 cases of fetal schizencephaly in terms of prenatal diagnostic features, and postnatal outcome. The database of prenatal diagnosis unit was searched for antenatally diagnosed cases with schizencephaly. Maternal characteristics, ultrasonography, prenatal-postnatal magnetic resonance imaging (MRI) findings, and postnatal outcome were noted. Of 5 cases, 2 had definitive prenatal diagnoses on ultrasound and 3 cases were diagnosed by fetal MRI. All cases had cerebral cortical migration anomalies including polymicrogyria, subependymal heterotopia, and lissencephaly, and 2 cases had additional extracranial malformations. Three cases showed regression of the cerebral clefts on follow-up postnatal MRIs. Three cases had moderate to severe psychomotor retardation, and 1 case needed repeated ventriculoperitoneal shunt operation due to hydrocephaly. Prenatal diagnosis of schizencephaly with ultrasonography is not straightforward and required further evaluation with fetal MRI. Additional cerebral anomalies worsen the prognosis of schizencephaly. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
