التفاصيل البيبلوغرافية
| العنوان: |
Sequential Evaluation of Coronary Flow Patterns after Primary Angioplasty in Acute Anterior ST-Elevation Myocardial Infarction Predicts Recovery of Left Ventricular Systolic Function. |
| المؤلفون: |
Sharif, Dawod1,2, Sharif ‐ Rasslan, Amal2, Makhoul, Nabeel1, Shefer, Arie1, Hassan, Amin1, Rosenschein, Uri1 |
| المصدر: |
Echocardiography. May2014, Vol. 31 Issue 5, p644-653. 10p. |
| مصطلحات موضوعية: |
*ANALYSIS of variance, *ANGIOGRAPHY, *ANGIOPLASTY, *CARDIAC output, *CORONARY circulation, *STATISTICAL correlation, *ECHOCARDIOGRAPHY, *LEFT heart ventricle, *HEART physiology, *HEART beat, *MYOCARDIAL infarction, *STATISTICS, *DATA analysis, *PRE-tests & post-tests, *PREDICTIVE tests, *INTER-observer reliability, *DATA analysis software, *DESCRIPTIVE statistics, RESEARCH evaluation |
| مستخلص: |
Background Function of the microcirculation after primary percutaneous coronary intervention ( PCI) is dynamic and contributes to unpredictability of recovery of left ventricular ( LV) systolic function. Aim This study was conducted to evaluate sequential Doppler velocity parameters of the left anterior descending coronary artery ( LAD) in predicting recovery of global and regional LV systolic function. Methods Thirty-five consecutive patients, 24 males, age 59 ± 12 years, with acute anterior ST-elevation myocardial infarction ( STEMI) who had primary PCI were studied. Thrombolysis in myocardial infarction ( TIMI) and myocardial blush grades were evaluated. Transthoracic echocardiographic ( TTE) studies, evaluation of left ventricular ejection fraction ( LVEF), LAD territory wall-motion score index ( WMSI), and sampling of LAD Doppler velocities up to 6 hours post- PCI, 48 hours postprocedure, and predischarge were performed. Results Thrombolysis in myocardial infarction grade before PCI averaged 0.86 ± 1.19 and post- PCI 2.89 ± 0.32, P < 0.05. Myocardial blush grade before PCI was 0.41 ± 0.98 and after PCI 2.22 ± 0.93, P < 0.05. Diastolic velocity deceleration time ( DDT) in the LAD early after PCI was less than 600 ms in 16 subjects. Immediately after PCI, in subjects with DDT > 600 ms, LVEF was 38.5 ± 6% and predischarge 49.2 ± 8.7%, P = 9.77 × 10−5 and LAD- WMSI decreased from 2 ± 0.38 to 1.4 ± 0.48, P = 0.000163. In subjects with DDT < 600 ms LAD- WMSI did not change significantly. Early and minimal LAD- DDT correlated with improvement in LV systolic function, r = 0.6, whereas post- PCI blush grade had lower correlation with LVEF, r = 0.39. Conclusions Global and regional LV systolic function after PCI in acute anterior MI can be predicted by LAD- DDT better than by post- PCI myocardial blush. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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