التفاصيل البيبلوغرافية
| العنوان: |
Telaprevir or boceprevir based therapy for chronic hepatitis C infection: Development of resistance-associated variants in treatment failure. |
| المؤلفون: |
Macartney, Malcolm J.1 malcolm.macartney@nhs.net, Irish, Dianne1, Bridge, Simon H.1, Garcia-Diaz, Ana1, Booth, Clare L.1, McCormick, Adele L.1, Labbett, Wendy1, Smith, Colette2, Velazquez, Carmen3, Tanwar, Sudeep4, Trembling, Paul4, Jacobs, Michael3, Dusheiko, Geoff3, Rosenberg, William3,4, Haque, Tanzina1 |
| المصدر: |
Antiviral Research. May2014, Vol. 105, p112-117. 6p. |
| مصطلحات موضوعية: |
*TELAPREVIR, *BOCEPREVIR, *VIRUS diseases, *HEPATITIS C treatment, *DRUG resistance, *VIRAL load, *THERAPEUTICS |
| مستخلص: |
Highlights: [•] The development of resistance is detected frequently in patients failing treatment. [•] Treatment failure is also linked to viral genotype. [•] IL28B genotype is an important indicator of outcome when using protease inhibitors. [•] Rate of viral load decay in previous treatment may predict outcome of PI treatment. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
