التفاصيل البيبلوغرافية
| العنوان: |
Predictors of Restenosis after Coronary Angioplasty. A Study on Demographic and Metabolic Variables. |
| المؤلفون: |
Johansen, Odd1, Abdelnoor, Michael2, Brekke, Magne3, Seljeflot, Ingebjørg2, Høstmark, Arne T.4, Arnesen, Harald1 |
| المصدر: |
Scandinavian Cardiovascular Journal. Apr2001, Vol. 35 Issue 2, p86-91. 6p. 4 Charts. |
| مصطلحات موضوعية: |
*CORONARY restenosis, *TRANSLUMINAL angioplasty, *CORONARY arterial radiography |
| مستخلص: |
Objective - The major concern about percutaneous transluminal coronary angioplasty (PTCA) is the high incidence of restenosis. Methods - Demographic, clinical and biochemical data were recorded 2 weeks prior to PTCA in 388 patients fulfilling the criteria for initial stenosis, successful PTCA, and angiographic follow-up after 6 months. Restenosis was evaluated by quantitative coronary angiography. Results - Variables predictive of restenosis in univariate analysis were diabetes mellitus, male gender, and the levels of high density lipoprotein (HDL) cholesterol, apolipoprotein A1 (Apo A1) and thio-barbituric acid-reactive substances (TBARS). In trend analysis through quartiles TBARS and fasting glucose levels were significantly associated with restenosis (p = 0.016 and 0.044, respectively), whereas the negative predictivity of Apo A1 and HDL-cholesterol were of borderline significance. In multivariate analysis male gender and diabetes mellitus showed predictivity of significance, and a negative predictivity was also apparent for HDL-cholesterol. Conclusion - We conclude that diabetes mellitus, male gender, and low HDL-cholesterol are predictors of restenosis 6 months after PTCA. In addition, TBARS may be a marker for the development of restenosis after PTCA. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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