التفاصيل البيبلوغرافية
| العنوان: |
Attenuation of Hydrogen Peroxide and Ferric Reducing/Antioxidant Power Serum Levels in Colorectal Cancer Patients with Intestinal Parasitic Infection. |
| المؤلفون: |
Samudi, Chandramathi1, Govind, Suresh Kumar1, Bustam, Anita Zarina2, Kuppusamy, Umah Rani3 umah@um.edu.my |
| المصدر: |
Malaysian Journal of Medical Sciences. Apr-Jun2009, Vol. 16 Issue 2, p15-20. 6p. 2 Charts. |
| مصطلحات موضوعية: |
*HYDROGEN peroxide, *ANTIOXIDANTS, *COLON cancer, *CANCER patients, *PARASITIC diseases, *MALONDIALDEHYDE, *OXIDATIVE stress |
| مستخلص: |
Background: This study assessed several common oxidative indices in subjects infected with intestinal parasites, as well as in colorectal cancer (CRC) patients both with and without intestinal parasites. Method: Serum levels of malondialdehyde (MDA), ferric reducing/antioxidant power (FRAP), and hydrogen peroxide (H²O²) were measured, as were plasma levels of advanced oxidation protein products (AOPP), all according to established methods. The presence of intestinal parasites was confirmed by stool examination. Results: All intestinal parasite-infected subjects and CRC patients showed the presence of oxidative stress. Thirty-six percent of the CRC patients had intestinal parasitic infections. The levels of H²O² and FRAP in parasite-infected subjects were significantly higher than in CRC patients, but these levels were significantly lower in the CRC patients with parasitic infections. Conclusion: Parasitic infection and CRC may contribute to oxidative stress independently, but when present together, the oxidative stress burden imposed by parasites may be attenuated. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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