دورية أكاديمية

Anti-MRSA Pyrone Derivative Products Isolated from Plant-Derived Fungus Aspergillus niger Pas67.

التفاصيل البيبلوغرافية
العنوان: Anti-MRSA Pyrone Derivative Products Isolated from Plant-Derived Fungus Aspergillus niger Pas67.
المؤلفون: Li, Wen-Yuan1,2,3 (AUTHOR) wenyuan59@126.com, Hu, Cheng-Cheng2 (AUTHOR), Yao, Hui-Na2 (AUTHOR), Ren, Jia-Qian2 (AUTHOR), Li, Zi-Han2 (AUTHOR), Lu, Ling-Pan1,2 (AUTHOR), Qiao, Min1,2 (AUTHOR), Shan, Bing-Bing2 (AUTHOR), Li, Jin-Ge2 (AUTHOR)
المصدر: Chemistry of Natural Compounds. May2024, Vol. 60 Issue 3, p415-418. 4p.
مصطلحات موضوعية: *MUPIROCIN, *ANTIBACTERIAL agents, *FUNGI, *METHICILLIN-resistant staphylococcus aureus, *ASPERGILLUS niger
مستخلص: A new pyrone derivative 11-hydroxypyrophen (1), together with pyrophen (2) and six naphtho-γ-pyrones (3–8), were obtained from the culture extract of Aspergillus niger Pas67. All isolated compounds were evaluated for their antibacterial activities against methicillin-resistant Staphylococcus aureus (MRSA). Compounds 4 and 8 showed significant antibacterial activity against MRSA with minimum inhibitory concentration values (MICs) of 25 and 16 μg/mL, while compounds 1 and 2 did not display anti-MRSA activity. [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00093130
DOI:10.1007/s10600-024-04340-4