التفاصيل البيبلوغرافية
| العنوان: |
Antioxidant activity of the main phenolics found in red fruits: An in vitro and in silico study. |
| المؤلفون: |
Gonçalves, Ana C.1,2 (AUTHOR), Falcão, Amílcar2,3 (AUTHOR), Alves, Gilberto1 (AUTHOR), Silva, Luís R.1,4,5 (AUTHOR) luisfarmacognosia@gmail.com, Flores-Félix, José David1,6 (AUTHOR) jdflores@usal.es |
| المصدر: |
Food Chemistry. Sep2024, Vol. 452, pN.PAG-N.PAG. 1p. |
| مصطلحات موضوعية: |
*PHENOLS, *BLUEBERRIES, *RADICALS (Chemistry), *SWEET cherry, *CAFFEIC acid, *FRUIT, *FLAVONOLS, *ANTHOCYANINS |
| مستخلص: |
• Antioxidant activity of the main phenolics found in sweet cherries and blueberries. • First report about DPPH, NO and O 2 − of 23 phenolic compounds. • Docking molecular and ADME studies regarding the most promising phenolics were done. The current study analysed the antioxidant capacity of the main phenolics found in red fruits. In total, there were analysed the antioxidant activity against 1,1-diphenyl-2-picrylhydrazyl radical, nitric oxide and superoxide radicals (DPPH, NO and O 2 −, respectively) of 23 phenolics. Regarding DPPH, anthocyanins, (-)-epicatechin and kaempferol 3- O -rutinoside were the most active, while isorhamnetin 3- O -glucoside was the least active. Anthocyanins, (-)-epicatechin, quercetin 3- O -glucoside and caffeic acid showed the strongest potential against NO, while ρ -hydroxybenzoic acid was the less efficient. Regarding the O 2 − assay, quercetin aglycone and their derivatives were the best ones, while cyanidin aglycone did not show any potential to quench this radical. To deeper explore the biological potential of the most promising compounds, docking molecular and ADME studies were also done. The obtained data is another support regarding the biological potential of phenolics and might be useful in encouraging their use and incorporation in new products. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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