التفاصيل البيبلوغرافية
| العنوان: |
Efficacy of 660nm Photobiomodulation in Burning Mouth Syndrome Management: A Single-Blind Quasi-Experimental Controlled Clinical Trial. |
| المؤلفون: |
Marotta, Bruno Munhoz1, Sugaya, Norberto Nobuo1, Hanna, Reem2,3,4, de Barros Gallo, Camila1 camilagallo@usp.br |
| المصدر: |
Photobiomodulation, Photomedicine & Laser Surgery. Mar2024, Vol. 42 Issue 3, p225-229. 5p. |
| مصطلحات موضوعية: |
*BURNING mouth syndrome, *PHOTOBIOMODULATION therapy, *CLINICAL trials, *PLACEBOS, *PAIN management, *OCEAN wave power |
| مستخلص: |
Background: Burning mouth syndrome (BMS) is characterized by a burning sensation of the oral mucosa without any evidence of clinical signs or underlining condition. Several treatment modalities have been utilized with various results and levels of evidence. Lately, photobiomodulation (PBM) has emerged as a noninvasive effective therapy due to its anti-inflammatory and biostimulatory effects, especially the low-power laser setting of red wavelength. Objective: This single-blind quasi-experimental controlled clinical trial aimed to evaluate the PBM effectiveness at a low level of red laser light in patients with BMS compared with sham control. Materials and methods: Thirty patients diagnosed with BMS were consecutively assigned to intervention (PBM therapy) and control (sham) groups. The protocol for PBM dosimetry was as follows: laser 660 nm; spot size: 0.04 cm2; power output: 100mW; emission mode: continuous wave; power density: 6 J/cm2; irradiation time: 10 sec per point within 1 cm2 surface area of the symptomatic area. The treatment protocol was based on once a week for a total of 10 sessions. Results: Our results showed no statistically significant difference in reduction of pain intensity between the two groups at all the evaluated timepoints during the course of treatment. However, in both groups, we observed a statistically significant reduction of maximum pain intensity of 50% compared with patient-self reporting before the treatment. Conclusions: Further randomized clinical trials to validate our positive results with a large sample size with a long-term follow-up and understanding further the sham placebo effect are warranted. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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