التفاصيل البيبلوغرافية
| العنوان: |
Iridium-catalysed hydroamination of internal homoallylic amines. |
| المؤلفون: |
Ho, An T.1 (AUTHOR), Vanable, Evan P.2 (AUTHOR), Miguel, Chelsea San1 (AUTHOR), Hull, Kami L.1,2 (AUTHOR) kamihull@utexas.edu |
| المصدر: |
Chemical Communications. 2/11/2024, Vol. 60 Issue 12, p1615-1618. 4p. |
| مصطلحات موضوعية: |
*AMINATION, *HYDROAMINATION, *ALIPHATIC amines, *AMINES, *ALKENES |
| مستخلص: |
An Ir-catalysed regioselective hydroamination of internal homoallylic amines is reported. Both cyclic and acyclic internal olefins undergo directed hydroamination reactions with both aromatic and cyclic aliphatic amines to afford a variety of 1,4-diamines in fair to excellent yields. Diastereoselectivity and mechanistic investigations support that for cyclic substrates the reactions are proceeding via trans-aminoiridation to form a 5-membered metalacyclic intermediate. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
