دورية أكاديمية

The Human Blood Fluke, Schistosoma mansoni, Harbors Bacteria Throughout the Parasite's Life Cycle.

التفاصيل البيبلوغرافية
العنوان: The Human Blood Fluke, Schistosoma mansoni, Harbors Bacteria Throughout the Parasite's Life Cycle.
المؤلفون: Formenti, Fabio1,2 (AUTHOR), Cortés, Alba1,3 (AUTHOR), Deiana, Michela2 (AUTHOR), Salter, Susannah1 (AUTHOR), Parkhill, Julian1 (AUTHOR), Berriman, Matt4,5 (AUTHOR), Rinaldi, Gabriel4,6 (AUTHOR) cc779@cam.ac.uk, Cantacessi, Cinzia1 (AUTHOR) cc779@cam.ac.uk
المصدر: Journal of Infectious Diseases. 11/1/2023, Vol. 228 Issue 9, p1299-1303. 5p.
مصطلحات موضوعية: *SCHISTOSOMA mansoni, *PARASITE life cycles, *HELMINTHS, *DNA probes, *IN situ hybridization, *HARBORS
مستخلص: While symbiotic relationships between invertebrates and bacteria have been extensively described, studies of microbial communities inhabiting parasitic worms remain scarce. Exploring the microbiota associated with helminths responsible for major infectious diseases will inform on parasite biology, host-pathogen interactions, and disease pathophysiology. We investigated the presence of microorganisms inhabiting tissues of the human parasite Schistosoma mansoni. In situ hybridization using a pan-bacterial 16S rRNA gene probe revealed bacteria colonizing key developmental stages that were successfully removed after antibiotic treatment of live parasites. Understanding the composition and function of the S. mansoni -associated microbiota may lead to the development of novel microbiome-targeting control strategies [ABSTRACT FROM AUTHOR]
قاعدة البيانات: Academic Search Index
الوصف
تدمد:00221899
DOI:10.1093/infdis/jiad288