التفاصيل البيبلوغرافية
| العنوان: |
Implantable nanostructured MEA with biphasic current stimulator for retinal prostheses. |
| المؤلفون: |
Han, Seungju1 (AUTHOR), Kim, Changhee1 (AUTHOR), Kim, Kangil1 (AUTHOR), Lee, Sangmin1,2 (AUTHOR) sangmlee@khu.ac.kr |
| المصدر: |
Technology & Health Care. 2023, Vol. 31 Issue 5, p1981-1995. 15p. |
| مصطلحات موضوعية: |
*PROSTHETICS, *MICROELECTRODES, *RETINAL blood vessels, *RETINA, *ELECTRODES |
| مستخلص: |
BACKGROUND: In retinal prosthetic systems on multi-channel microelectrodes to effectively stimulate retinal neurons, the electrode-electrolyte interface impedance of a microelectrode should be minimized to drive sufficiently large current at a given supply voltage. OBJECTIVE: This paper presents the fabrication of the nanostructured microelectrode array with simplified fabrication and its characteristic evaluation using biphasic current stimulator. METHODS: The nanostructured microelectrodes with the base diameter of 25 μ m, 50 μ m, 75 μ m are fabricated, and the maximum allowable current injection limits are measured to verify the estimated injection limit. Also, a biphasic stimulator has been fabricated using the 2-stage amplifier and 4 switches based on a stimulator cell. The adjustable load resistance is adopted to control between 5 k Ω to 20 k Ω , and the biphasic stimulator can drive the stimulation current between 50 uA and 200 uA. RESULTS: The proposed electrode-electrolyte interface impedance of the fabricated nanostructured microelectrode is 3178 Ω , 1218 Ω and 798.8 Ω for electrodes with diameter of 25 μ m, 50 μ m, 75 μ m, respectively. CONCLUSION: This paper shows the advantages of the nanostructured microelectrode arrays for high resolution retinal prostheses, which could be a basic experiment for artificial retina research. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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