التفاصيل البيبلوغرافية
| العنوان: |
Four-Year Increase in Step Cadence Is Associated with Improved Cardiometabolic Health in People with a History of Prediabetes. |
| المؤلفون: |
MCBRIDE, PHILIP1,2 ty20@le.ac.uk, HENSON, JOSEPH1,2, EDWARDSON, CHARLOTTE L.1,2, MAYLOR, BENJAMIN1,2, DEMPSEY, PADDY C.1,2, ROWLANDS, ALEX V.1,2, DAVIES, MELANIE J.1,2, KHUNTI, KAMLESH1,3, YATES, THOMAS1,2 |
| المصدر: |
Medicine & Science in Sports & Exercise. Sep2023, Vol. 55 Issue 9, p1601-1609. 9p. |
| مصطلحات موضوعية: |
*BIOMARKERS, *CARDIOVASCULAR diseases risk factors, *CONFIDENCE intervals, *DESCRIPTIVE statistics, *REPEATED measures design, *DEMOGRAPHY, *DATA analysis software, *PREDIABETIC state, *LONGITUDINAL method, *DISEASE complications |
| مستخلص: |
Purpose: To investigate associations between 4-yr change in step cadence and markers of cardiometabolic health in people with a history of prediabetes and to explore whether these associations are modified by demographic factors. Methods: In this prospective cohort study, adults, with a history of prediabetes, were assessed for markers of cardiometabolic health (body mass index, waist circumference, high-density lipoprotein cholesterol [HDL-C], low-density lipoprotein cholesterol [LDL-C], triglycerides, and glycated hemoglobin A1c [HbA1c]), and free-living stepping activity (activPAL3™) at baseline, 1 yr, and 4 yr. Brisk steps per day were defined as the number of steps accumulated at ≥100 steps per minute and slow steps per day as those accumulated at <100 steps per minute; the mean peak stepping cadence during the most active 10 minutes of the day was also derived. Generalized estimating equations examined associations between 4-yr change in step cadence and change in cardiometabolic risk factors, with interactions by sex and ethnicity. Results: Seven hundred ninety-four participants were included (age, 59.8 ± 8.9 yr; 48.7% women; 27.1% ethnic minority; total steps per day, 8445 ± 3364; brisk steps per day, 4794 ± 2865; peak 10-min step cadence, 128 ± 10 steps per minute). Beneficial associations were observed between change in brisk steps per day and change in body mass index, waist circumference, HDL-C, and HbA1c. Similar associations were found between peak 10-min step cadence and HDL-C and waist circumference. Interactions by ethnicity revealed change in brisk steps per day and change in peak 10-min step cadence had a stronger association with HbA1c in White Europeans, whereas associations between change in 10-min peak step cadence with measures of adiposity were stronger in South Asians. Conclusions: Change in the number of daily steps accumulated at a brisk pace was associated with beneficial change in adiposity, HDL-C, and HbA1c; however, potential benefits may be dependent on ethnicity for outcomes related to HbA1c and adiposity. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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