التفاصيل البيبلوغرافية
| العنوان: |
幼童脑干形态学与增龄发育的数字化特征. |
| العنوان البديل: |
Digital characteristics of brainstem morphology and age-related development in young children. |
| المؤلفون: |
刘亚楠1, 王 星2,3, 李 琨2,3, 孙瑞芬4, 马雪英5, 赵 磊5, 刘宇航1, 杨 洋1, 郝韵腾1, 李梓瑜1, 张少杰2,3, 李志军2,3 |
| المصدر: |
Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu. 4/18/2024, Vol. 28 Issue 11, p1730-1736. 7p. |
| مصطلحات موضوعية: |
*MEDULLA oblongata, *MESENCEPHALON, *CHILD development, *MAGNETIC resonance imaging, *AGE groups, *BRAIN stem |
| الملخص (بالإنجليزية): |
BACKGROUND: Previous brain studies have mostly focused on adults and fetuses, and the developmental characteristics of young children's brainstems have rarely been studied. OBJECTIVE: To observe the brainstem development characteristics of healthy young children and to explore the age-related differences and their correlation with sex. METHODS: From January 2019 to April 2022, a retrospective study of 3.0T MRI images of 174 children aged 2 to 6 years in the Affiliated Hospital of Inner Mongolia Medical University was conducted, and the median sagittal diameter, area and angle of the brainstem (including midbrain, pons and medulla oblongata) were measured. RESULTS AND CONCLUSION: There is an age-related increase in the anterior and posterior diameters of the midbrain, pons and medulla oblongata in the 2-5 years old group as well as in the longitudinal diameter and area of the midbrain, pons and medulla oblongata in the 2-6 years old group. Except for the longitudinal diameter of the medulla oblongata, all others show a positive correlation with age (r > 0, P < 0.05). In the 2-3 years old group and 4-5 years old group, the children are in the rapid growth and development stage, and these two age groups can be used as the key observation indicators for the development of young children. The anterior-posterior diameter, longitudinal diameter, area of the pons and total brainstem area are strongly correlated with age, which can be used as the key observation indicators for the brainstem development in young children. [ABSTRACT FROM AUTHOR] |
| Abstract (Chinese): |
背景：既往对脑干研究多集中于成人和胎儿，而对国人幼童脑干的增龄发育特征研究甚少。 目的：观测健康幼童脑干发育特征，探究其增龄差异及其与性别间的相关性。 方法：2019 年 1 月至 2022 年 4 月对内蒙古医科大学附属医院174例 2-6 岁幼童颅颈部 3.0T MRI 图像行回顾性研究，测量脑干 (含中脑、脑桥、延 髓) 正中矢状面径线、面积和角度。 结果与结论：中脑、脑桥、延髓前后径在2-5岁组，中脑、脑桥、延髓纵径和面积在 2-6 岁组总体随增龄呈递增趋势，除延髓纵径外均呈正 相关 (r > 0，P < 0.05)，在 2-3 岁组、4-5 岁组期间处于快速生长发育阶段，这 2 个年龄组可作为幼童发育重点观测指标；脑桥前后径、纵径、 面积和脑干总面积与年龄相关性较强，可作为其脑干发育重点观测指标。 [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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