التفاصيل البيبلوغرافية
| العنوان: |
Diagnostic yield and safety of ultrasound-guided percutaneous testicular biopsies in children. |
| المؤلفون: |
Minhas, Kishore1 (AUTHOR), Roebuck, Derek J.1,2,3 (AUTHOR), Sebire, Neil4 (AUTHOR), Cho, Alexander5 (AUTHOR), Patel, Premal A.1 (AUTHOR) premal.patel@gosh.nhs.uk |
| المصدر: |
Pediatric Radiology. Aug2023, Vol. 53 Issue 9, p1903-1910. 8p. 2 Color Photographs, 1 Chart. |
| مصطلحات موضوعية: |
*CHILDREN'S hospitals, *BIOPSY, *GRANULOSA cell tumors |
| مستخلص: |
Background: Traditionally, testicular biopsy is performed using an open surgical approach. Ultrasound-guided percutaneous biopsy is a less invasive alternative and can be performed in children. Objective: The aim of this study is to report our technique and to assess the diagnostic accuracy and safety of ultrasound-guided percutaneous biopsy of testicular masses in children. Materials and methods: This is a 16-year retrospective review of ultrasound-guided percutaneous testicular biopsies at a single pediatric hospital. Results: We performed nine ultrasound-guided testicular biopsies in 9 patients (median age: 3 years, range: 4 months–11 years; median weight: 20.9 kg, range: 8.4–35 kg; median volume of testicular lesion biopsied: 4.4 mL, range: 1.2–17 mL). A percutaneous co-axial technique was used for 5/9 biopsies with absorbable gelatin sponge tract embolization performed in 4 of those biopsies. A non-co-axial technique was used in 4/9 biopsies. A median of three cores, range 2–6, were obtained. The diagnostic yield was 89% with one biopsy yielding material suggestive of, but insufficient for, a definitive diagnosis. The most common histological diagnosis was leukemic infiltration, occurring in 6/9 biopsies. Of the remaining three biopsies, one biopsy was suggestive of, but not confirmatory for, juvenile granulosa cell tumor and two biopsies confirmed normal testicular tissue; the long-term follow-up of which demonstrated normal growth and no lasting damage. There was one (clinically insignificant) complication out of nine biopsies (11%, 95% confidence interval 0–44%): a mild, self-resolving scrotal hematoma. Conclusion: Ultrasound-guided testicular biopsy can be performed safely in children as an alternative to open surgical biopsy, with a high diagnostic yield and low complication rate. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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