التفاصيل البيبلوغرافية
| العنوان: |
Latex allergy can induce clinical reactions to specific foods. |
| المؤلفون: |
Beezhold, D. H.1, Sussman, G. L.2, Liss, G. M.2,3, Chang, N.-S.1 |
| المصدر: |
Clinical & Experimental Allergy. Apr1996, Vol. 26 Issue 4, p416-422. 7p. |
| مصطلحات موضوعية: |
*LATEX allergy, *FOOD allergy, *ALLERGENS, *PLANT proteins, *CARRIER proteins, *IMMUNOLOGY |
| مستخلص: |
Objective The purpose of this study was to investigate crossreactivity between latex and foods, to identify crossreacting IgE binding proteins, and to assess the clinical significance. Methods Forty-seven latex allergic patients and 46 non-latex allergic patient controls were studied. Allergen sensitization was determined by skin-prick testing (SPT) and allergenic proteins were identified by immunoblot reactivity and amino acid sequence analysis. Results Immunological reactivity to foods was found to be common, occurring in 33 latex-allergic individuals but in only seven controls (P < 0.000001); 100 of 376 (27%) food skin-prick tests were positive in the latex-allergic subjects. Twenty-seven out of 100 positive food SPTs were associated with clinical symptoms. Seventeen patients manifested a clinical allergy to at least one food including 11 with anaphylaxis, and 14 with local sensitivity reactions. Positive food skin tests occurred most frequently with avocado (53%), potato (40%), banana (38%), tomato (28%), chestnut (28%), and kiwi (17%). Latex-allergic patients (23%) recognize a protein that had sequence homology to a broad class of plant proteins known as patatins. Crossreactivity between latex and several potato proteins was observed by immunoblot inhibition analysis. Conclusions Sensitization to latex has extensive crossreactivity with certain foods and leads to clinical allergic reactions. Potatoes and tomatoes are newly reported cross-reacting foods. Plant proteins with structural homology to latex proteins may predispose to food allergy. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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