التفاصيل البيبلوغرافية
| العنوان: |
Cannabis Inhalation Acutely Reduces Muscle Sympathetic Nerve Activity in Humans. |
| المؤلفون: |
Cheung, Christian P.1 (AUTHOR) ccheun05@uoguelph.ca, Nardone, Massimo1 (AUTHOR) mnardo01@uoguelph.ca, Lee, Jordan B.1 (AUTHOR) jlee33@uoguelph.ca, Baker, Ryleigh E.1 (AUTHOR), Millar, Philip J.1,2 (AUTHOR) pmillar@uoguelph.ca, Burr, Jamie F.1 (AUTHOR) burrj@uoguelph.ca |
| المصدر: |
Circulation. 12/20/2022, Vol. 146 Issue 25, p1972-1974. 3p. |
| مصطلحات موضوعية: |
*DIASTOLIC blood pressure, *NERVES, *CARDIOVASCULAR system, *SYSTOLIC blood pressure, *CARDIAC output |
| مستخلص: |
Cannabis inhalation increased mean arterial pressure (79±7 vs 84±8 mmHg), systolic blood pressure (109±8 vs 113±10 mmHg), and diastolic blood pressure (64±7 vs 69±8 mmHg; all I P i <0.04). Keywords: baroreflex; blood pressure; cannabis; dronabinol EN baroreflex blood pressure cannabis dronabinol 1972 1974 3 12/26/22 20221220 NES 221220 The growing acceptance and use of recreational cannabis, combined with the recognition of an incomplete understanding of the cardiovascular effects in humans, has led to the urgent call for further scientific investigation.[1] The current consensus is that cannabis and its primary psychotropic compound -9-tetrahydrocannbinol (THC) cause activation of the sympathetic nervous system.[1],[2] This interpretation is based largely on evidence that cannabis causes an acute elevation in heart rate that is attenuated by -adrenoreceptor blockade.[2] Despite evidence supporting increased cardiac sympathetic activity, measurement of sympathetic outflow directed towards the vasculature has not been reported. [Extracted from the article] |
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