التفاصيل البيبلوغرافية
| العنوان: |
Review on atmospheric pressure ionization sources for gas chromatography-mass spectrometry. Part I: Current ion source developments and improvements in ionization strategies. |
| المؤلفون: |
Ayala-Cabrera, Juan F.1,2 (AUTHOR) juan.ayala-cabrera@uni-due.de, Montero, Lidia1,2 (AUTHOR), Meckelmann, Sven W.1,2 (AUTHOR), Uteschil, Florian1,2 (AUTHOR), Schmitz, Oliver J.1,2 (AUTHOR) oliver.schmitz@uni-due.de |
| المصدر: |
Analytica Chimica Acta. Jan2023, Vol. 1238, pN.PAG-N.PAG. 1p. |
| مصطلحات موضوعية: |
*ATMOSPHERIC ionization, *GAS chromatography/Mass spectrometry (GC-MS), *ATMOSPHERIC pressure, *ION sources, *MASS spectrometers, *IONS |
| مستخلص: |
The use of atmospheric pressure ionization (API) sources has become very popular for gas chromatography-mass spectrometry (GC-MS) determinations. GC-API-MS shows important advantages over traditional vacuum ionization sources such as a lower fragmentation preserving the molecular or quasi-molecular ion, the combination of GC separations with advanced mass spectrometers typically developed for liquid chromatography (LC) systems, a significantly higher sensitivity, or the reduction of costs due to the capability to use the same MS for both LC- and GC- couplings. For these reasons, the development of new API sources and GC-API-MS platforms has exponentially increased during the last years. Thus, this review is mainly focused on the last advances in GC-API-MS instrumentation. New setups and couplings on extensively reported API techniques as well as the development of new API sources for GC-MS coupling are thoroughly discussed. Moreover, novel ionization strategies have been reviewed to overcome some of the drawbacks of GC-API-MS methodologies. [Display omitted] • New API set-ups for GC-MS improve detectability, selectivity and precision. • New API sources based on plasma, laser or chemical ionization has been developed. • Controlled addition of modifiers may enable more selective and sensitive methods. • GC-MS data combining API and EI enhance the confidence level in non-target analysis. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
