التفاصيل البيبلوغرافية
| العنوان: |
CalScope: Monitoring Severe Acute Respiratory Syndrome Coronavirus 2 Seroprevalence From Vaccination and Prior Infection in Adults and Children in California May 2021–July 2021. |
| المؤلفون: |
Mehrotra, Megha L1 (AUTHOR) megha.mehrotra@cdph.ca.gov, Lim, Esther1 (AUTHOR), Lamba, Katherine1 (AUTHOR), Kamali, Amanda1 (AUTHOR), Lai, Kristina W1 (AUTHOR), Meza, Erika1 (AUTHOR), Szeto, Irvin2 (AUTHOR), Robinson, Peter3 (AUTHOR), Tsai, Cheng-ting3 (AUTHOR), Gebhart, David3 (AUTHOR), Fonseca, Noemi3 (AUTHOR), Martin, Andrew B2 (AUTHOR), Ley, Catherine2 (AUTHOR), Scherf, Steve4 (AUTHOR), Watt, James1 (AUTHOR), Seftel, David3 (AUTHOR), Parsonnet, Julie2 (AUTHOR), Jain, Seema1 (AUTHOR) |
| المصدر: |
Open Forum Infectious Diseases. Jul2022, Vol. 9 Issue 7, p1-10. 10p. |
| مصطلحات موضوعية: |
*SARS-CoV-2 |
| مصطلحات جغرافية: |
CALIFORNIA |
| مستخلص: |
Background Understanding the distribution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibodies from vaccination and/or prior infection is critical to the public health response to the pandemic. CalScope is a population-based serosurvey in 7 counties in California. Methods We invited 200 000 randomly sampled households to enroll up to 1 adult and 1 child between April 20, 2021 and June 16, 2021. We tested all specimens for antibodies against SARS-CoV-2 nucleocapsid and spike proteins, and each participant completed an online survey. We classified participants into categories: seronegative, antibodies from infection only, antibodies from infection and vaccination, and antibodies from vaccination only. Results A total of 11 161 households enrolled (5.6%), with 7483 adults and 1375 children completing antibody testing. As of June 2021, 33% (95% confidence interval [CI], 28%–37%) of adults and 57% (95% CI, 48%–66%) of children were seronegative; 18% (95% CI, 14%–22%) of adults and 26% (95% CI, 19%–32%) of children had antibodies from infection alone; 9% (95% CI, 6%–11%) of adults and 5% (95% CI, 1%–8%) of children had antibodies from infection and vaccination; and 41% (95% CI, 37%–45%) of adults and 13% (95% CI, 7%–18%) of children had antibodies from vaccination alone. Conclusions As of June 2021, one third of adults and most children in California were seronegative. Serostatus varied regionally and by demographic group. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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