التفاصيل البيبلوغرافية
| العنوان: |
Real-World Use of a New Hybrid Closed Loop Improves Glycemic Control in Youth with Type 1 Diabetes. |
| المؤلفون: |
Messer, Laurel H.1 (NURSE) laurel.messer@cuanschutz.edu, Berget, Cari1 (NURSE), Pyle, Laura1 (AUTHOR), Vigers, Timothy1 (AUTHOR), Cobry, Erin1 (AUTHOR), Driscoll, Kimberly A.2 (AUTHOR), Forlenza, Gregory P.1 (AUTHOR) |
| المصدر: |
Diabetes Technology & Therapeutics. Dec2021, Vol. 23 Issue 12, p837-843. 7p. |
| مصطلحات موضوعية: |
*TYPE 1 diabetes, *GLYCEMIC control, *PEDIATRIC clinics, *INSULIN pumps, *GLYCOSYLATED hemoglobin |
| مستخلص: |
Objective: To describe real-world outcomes for youth using the Tandem t:slim X2 insulin pump with Control-IQ technology ("Control-IQ") for 6 months at a large pediatric clinic. Methods: Youth with type 1 diabetes, who started Control-IQ for routine care, were prospectively followed. Data on system use and glycemic control were collected before Control-IQ start, and at 1, 3, and 6 months after start. Mixed models assessed change across time; interactions with baseline hemoglobin A1c (HbA1c) and age were tested. Results: In 191 youth (median age 14, 47% female, and median HbA1c 7.6%), percent time with glucose levels 70-180 mg/dL (time-in-range [TIR]) improved from 57% at baseline to 66% at 6 months (P < 0.001). The proportion of participants reaching TIR target (>70%) doubled from 23.5% at baseline to 47.8% at 3 months, sustaining at 46.7% at 6 months (P < 0.001). Glucose management indicator (approximation of HbA1c) improved from 7.5% at baseline to 7.1% at 3 months and 7.2% at 6 months (P < 0.001). Those with higher baseline HbA1c experienced the most substantial improvements in glycemic control. Percent time using the Control-IQ feature was 86.4% at 6 months, and <4% of cohort discontinued use. Conclusion: The Control-IQ system clinically and significantly improved glycemic control in a large sample of youth. System use was high at 6 months, with only a small proportion discontinuing use, indicating potential for sustaining results long term. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
