التفاصيل البيبلوغرافية
| العنوان: |
Colocalization of tracks from boron neutron capture reactions and images of isolated cells. |
| المؤلفون: |
Postuma, Ian1 (AUTHOR) ian.postuma@pv.infn.it, Sommi, Patrizia2 (AUTHOR), Vitali, Agostina3 (AUTHOR), Shu, Diyun4 (AUTHOR), Martino, Greta di3 (AUTHOR), Cansolino, Laura1,5 (AUTHOR), Ferrari, Cinzia1,5 (AUTHOR), Ricci, Vittorio2 (AUTHOR), Magni, Chiara1,6 (AUTHOR), Protti, Nicoletta1 (AUTHOR), Fatemi, Setareh1 (AUTHOR), Tamburini, Umberto Anselmi3 (AUTHOR), Bortolussi, Silva1,6 (AUTHOR), Altieri, Saverio1,6 (AUTHOR) |
| المصدر: |
Applied Radiation & Isotopes. Jan2021, Vol. 167, pN.PAG-N.PAG. 1p. |
| مصطلحات موضوعية: |
*NEUTRON capture, *ALPHA rays, *BORON-neutron capture therapy, *CELL imaging, *NUCLEAR track detectors, *LITHIUM-ion batteries |
| مستخلص: |
In Boron Neutron Capture Therapy, the boronated drug plays a leading role in delivering a lethal dose to the tumour. The effectiveness depends on the boron macroscopic concentration and on its distribution at sub-cellular level. This work shows a way to colocalize alpha particles and lithium ions tracks with cells. A neutron autoradiography technique is used, which combines images of cells with images of tracks produced in a solid-state nuclear track detector. • Overlay of tracks from the 10B (n,α)7Li reaction over cells. • An affordable technique to study newly formulated 10B drugs. • Cells can be seeded directly on a CR39. • High resolution autoradiography limited by track diameter of ≈ 1 μm. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
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