التفاصيل البيبلوغرافية
| العنوان: |
Molecular characterization of the porcine gene CAPNS1 encoding the small subunit 1 of calpain on SSC6q1.1→q1.2. |
| المؤلفون: |
Drögemüller, C.1, Leeb, T.1 Tosso.Leeb@tiho-hannover.de |
| المصدر: |
Cytogenetic & Genome Research. 2002, Vol. 98 Issue 2/3, p206-209. 4p. 3 Charts, 1 Graph. |
| مصطلحات موضوعية: |
*GENES, *LIVESTOCK genetics, *ANIMAL genetics, *GENETIC polymorphisms, *CALPAIN |
| مستخلص: |
The CAPNS1 gene encodes the small subunit of the calpain proteases. Cloning and characterization of the porcine CAPNS1 gene revealed a highly conserved organization with respect to other mammalian CAPNS1 orthologs. The porcine gene consists of 11 exons spanning approximately 7.3 kb and codes for a peptide of 266 amino acids. Analysis of the naturally occurring variation of the CAPNS1 gene in different pig breeds revealed six SNPs and four small insertion/deletion polymorphisms. The CAPNS1 gene is located immediately adjacent to the COX7A1 gene on SSC6q1.1→q1.2. Copyright © 2002 S. Karger AG, Basel [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
