التفاصيل البيبلوغرافية
| العنوان: |
Sesquiterpenes from the essential oil of Curcuma wenyujin and their inhibitory effects on nitric oxide production. |
| المؤلفون: |
Xia, Guiyang1, Zhou, Li1, Ma, Jianghao1, Wang, Ying1, Ding, Liqin2, Zhao, Feng3, Chen, Lixia1 syzyclx@163.com, Qiu, Feng1,2 fengqiu20070118@163.com |
| المصدر: |
Fitoterapia. Jun2015, Vol. 103, p143-148. 6p. |
| مصطلحات موضوعية: |
*ALTERNATIVE medicine, *ANIMAL experimentation, *ANTI-inflammatory agents, *BIOLOGICAL models, *PHYSICAL & theoretical chemistry, *ESSENTIAL oils, *MACROPHAGES, *MEDICINAL plants, *MICE, *NITRIC oxide, *SPECTRUM analysis, *VEGETABLE oils, *PLANT extracts, *DESCRIPTIVE statistics, *IN vitro studies, *PHARMACODYNAMICS |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
Three new sesquiterpenes including a new elemane-type sesquiterpene, 5 βH -elem-1,3,7,8-tetraen-8,12-olide ( 1 ), and two new carabrane-type sesquiterpenes, 7 α ,11-epoxy-6 α -methoxy-carabrane-4,8-dione ( 2 ) and 8,11-epidioxy-8-hydroxy-4-oxo-6-carabren ( 3 ), together with eight known sesquiterpenes ( 4 – 11 ) were isolated from Curcuma wenyujin Y. H. Chen et C. Ling. Their structures were elucidated based on extensive spectroscopic analyses. A possible biogenetic scheme for the related compounds was postulated. All of the isolated compounds were tested for inhibitory activity against LPS-induced nitric oxide production in RAW 264.7 macrophages. Meanwhile, preliminary structure–activity relationships for these compounds are discussed. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
