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Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet

التفاصيل البيبلوغرافية
العنوان: Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet
المؤلفون: G. Godoy, C.C.O. Bernardo, L. Casagrande, M.L.M. Sérgio, J.N. Zanoni, J.V.C.M. Perles, R. Curi, R.B. Bazotte
المصدر: Brazilian Journal of Medical and Biological Research, Vol 56 (2023)
بيانات النشر: Associação Brasileira de Divulgação Científica, 2023.
سنة النشر: 2023
المجموعة: LCC:Medicine (General)
LCC:Biology (General)
مصطلحات موضوعية: Flaxseed oil, Omega 3 polyunsaturated fatty acids, Liver fibrosis, Hepatocellular ballooning, Hepatic steatosis, NAFLD, Medicine (General), R5-920, Biology (General), QH301-705.5
الوصف: The impact of linseed oil as a lipid source on liver disease induced by a high-carbohydrate diet (HCD) was evaluated. Adult male Swiss mice received an HCD containing carbohydrates (72.1%), proteins (14.2%), and lipids (4.0%). The Control HCD group (HCD-C) received an HCD containing lard (3.6%) and soybean oil (0.4%) as lipid sources. The L10 and L100 groups received an HCD with 10 and 100% linseed oil as lipid sources, respectively. A group of mice were euthanized before receiving the diets (day 0) and the remaining groups after 56 days of receiving the diets (HCD-C, L10, and L-100 groups). Morphological and histopathological analyses, as well as collagen deposition were evaluated. Perivenous hepatocytes (PVH) of the HCD-C group were larger (P
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1414-431X
1414-431x
العلاقة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100664&tlng=enTest; https://doaj.org/toc/1414-431XTest
DOI: 10.1590/1414-431x2023e12927
الوصول الحر: https://doaj.org/article/71c3864bc28b4d009d138cf75f3b6f3eTest
رقم الانضمام: edsdoj.71c3864bc28b4d009d138cf75f3b6f3e
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:1414431X
1414431x
DOI:10.1590/1414-431x2023e12927