Distribution of Chlamydia trachomatis ompA genovars and the new variant of C. trachomatis in the Göteborg area, Sweden.
| العنوان: | Distribution of Chlamydia trachomatis ompA genovars and the new variant of C. trachomatis in the Göteborg area, Sweden. |
|---|---|
| المؤلفون: | Lagergård, Teresa, 1946, Hadad, R, Tunbäck, Petra, 1965, Lindholm, L, Löwhagen, Gun-Britt, 1942, Unemo, Magnus |
| المصدر: | European journal of clinical microbiology & infectious diseases. 29(5):609-611 |
| مصطلحات موضوعية: | Microbiology in the medical area, Mikrobiologi inom det medicinska området, Dermatology and Venereal Diseases, Dermatologi och venereologi, Adolescent, Adult, Bacterial Outer Membrane Proteins/*genetics, Chi-Square Distribution, Chlamydia Infections/*epidemiology/*microbiology, Chlamydia trachomatis/*genetics/isolation & purification, Female, Humans, Male, Middle Aged, Mutation, Sweden/epidemiology |
| الوصف: | The aims of this study were to assess the proportion of the new variant of Chlamydia trachomatis (nvCT) and the distribution of ompA genovars among C. trachomatis-positive patients in the Göteborg area, Sweden. Consecutive urine samples positive for C. trachomatis using BD ProbeTec ET (177 patients, 88 men and 89 women) were collected. An nvCT-specific real-time polymerase chain reaction (PCR) assay was used to investigate the nvCT prevalence. To identify the genovars, a 990-bp ompA DNA segment from 105 specimens was sequenced. Seventeen percent (30/177) of all specimens contained nvCT. Nine different genovars were identified. About 50% were of genovar E, followed by F 16%, G 11%, K 8%, and D 5%, representing about 90% of the specimens in Göteborg. The occurrence of nvCT and the dominance of genovar E in Göteborg is similar to those in other areas of Sweden. To cover about 90% of the C. trachomatis infections in Sweden, the serovars D, E, F, G, and K should be included in future vaccines based on the major outer membrane protein. |
| الوصول الحر: | https://gup.ub.gu.se/publication/120868Test |
| قاعدة البيانات: | SwePub |
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