دورية أكاديمية

Cuticular drusen associated with aneurysmal type 1 neovascularization (polypoidal choroidal vasculopathy)

التفاصيل البيبلوغرافية
العنوان: Cuticular drusen associated with aneurysmal type 1 neovascularization (polypoidal choroidal vasculopathy)
المؤلفون: Serena Fragiotta, Talia R. Kaden, K. Bailey Freund
المصدر: International Journal of Retina and Vitreous, Vol 4, Iss 1, Pp 1-5 (2018)
بيانات النشر: BMC, 2018.
سنة النشر: 2018
المجموعة: LCC:Ophthalmology
مصطلحات موضوعية: Cuticular drusen, Polypoidal choroidal vasculopathy, Aneurysmal type 1 neovascularization, Optical coherence tomography angiography, Fluorescein angiography, Indocyanine green angiography, Ophthalmology, RE1-994
الوصف: Abstract Background Aneurysmal type 1 neovascularization (AT1) is a term recently introduced to better describe the aneurysmal dilatation that may arise from neovascular lesions, more commonly known as polypoidal choroidal vasculopathy. The proposed term, AT1, includes an expanded clinical spectrum of aneurysmal (polypoidal) lesions observed in both different ethnicities and associated with varied clinical phenotypes. Case presentation A 61-year-old woman of European descent was referred for a new, asymptomatic retinal hemorrhage found on routine examination. Ophthalmoscopy revealed cuticular drusen in both eyes best appreciated on fundus autofluorescence, and a hemorrhagic retinal pigment epithelium detachment above the superior arcade in the right eye. In the fellow eye, a reddish appearing pigment epithelial detachment was noted nasal to the optic nerve. Indocyanine green angiography showed findings of AT1 in both eyes. Optical coherence tomography angiography showed intrinsic flow signal within the aneurysmal lesions. Conclusions Eyes with cuticular drusen may develop AT1 which, to our knowledge, has not been described. This is an important observation because the documented coexistence of AT1 in the setting of a variant of age-related macular degeneration lends supports to this new understanding of AT1 as a growth pattern of neovascular tissue proliferating between the RPE and Bruch membrane, rather than as a distinct disease entity.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2056-9920
العلاقة: http://link.springer.com/article/10.1186/s40942-018-0148-5Test; https://doaj.org/toc/2056-9920Test
DOI: 10.1186/s40942-018-0148-5
الوصول الحر: https://doaj.org/article/f59375d5969a4d6e930528fa224d7687Test
رقم الانضمام: edsdoj.f59375d5969a4d6e930528fa224d7687
قاعدة البيانات: Directory of Open Access Journals
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