دورية أكاديمية
Characterization of Individualized Glycemic Excursions during a Standardized Bout of Hypoglycemia-Inducing Exercise and Subsequent Hypoglycemia Treatment—A Pilot Study
| العنوان: | Characterization of Individualized Glycemic Excursions during a Standardized Bout of Hypoglycemia-Inducing Exercise and Subsequent Hypoglycemia Treatment—A Pilot Study |
|---|---|
| المؤلفون: | Jan Brož, Matthew D. Campbell, Jana Urbanová, Marisa A. Nunes, Ludmila Brunerová, Dario Rahelić, Denisa Janíčková Žďárská, Arian Taniwall, Marek Brabec, Vojtěch Berka, Juraj Michalec, Jan Polák |
| المصدر: | Nutrients, Vol 13, Iss 11, p 4165 (2021) |
| بيانات النشر: | MDPI AG, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Nutrition. Foods and food supply |
| مصطلحات موضوعية: | type 1 diabetes, exercise, hypoglycemia, insulin therapy, glycemic excursion, hypoglycemia treatment, Nutrition. Foods and food supply, TX341-641 |
| الوصف: | The glycemic response to ingested glucose for the treatment of hypoglycemia following exercise in type 1 diabetes patients has never been studied. Therefore, we aimed to characterize glucose dynamics during a standardized bout of hypoglycemia-inducing exercise and the subsequent hypoglycemia treatment with the oral ingestion of glucose. Ten male patients with type 1 diabetes performed a standardized bout of cycling exercise using an electrically braked ergometer at a target heart rate (THR) of 50% of the individual heart rate reserve, determined using the Karvonen equation. Exercise was terminated when hypoglycemia was reached, followed by immediate hypoglycemia treatment with the oral ingestion of 20 g of glucose. Arterialized blood glucose (ABG) levels were monitored at 5 min intervals during exercise and for 60 min during recovery. During exercise, ABG decreased at a mean rate of 0.11 ± 0.03 mmol/L·min−1 (minimum: 0.07, maximum: 0.17 mmol/L·min−1). During recovery, ABG increased at a mean rate of 0.13 ± 0.05 mmol/L·min−1 (minimum: 0.06, maximum: 0.19 mmol/L·min−1). Moreover, 20 g of glucose maintained recovery from hypoglycemia throughout the 60 min postexercise observation window. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2072-6643 |
| العلاقة: | https://www.mdpi.com/2072-6643/13/11/4165Test; https://doaj.org/toc/2072-6643Test |
| DOI: | 10.3390/nu13114165 |
| الوصول الحر: | https://doaj.org/article/982f9757b1bb41d3834cde83761ebc84Test |
| رقم الانضمام: | edsdoj.982f9757b1bb41d3834cde83761ebc84 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | ResultId |
1 |
|---|---|
| Header |
edsdoj Directory of Open Access Journals edsdoj.982f9757b1bb41d3834cde83761ebc84 921 3 Academic Journal academicJournal 920.850952148438 |
| PLink |
https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsdoj&AN=edsdoj.982f9757b1bb41d3834cde83761ebc84&custid=s6537998&authtype=sso |
| FullText |
Array
(
[Availability] => 0
)
Array ( [0] => Array ( [Url] => https://doaj.org/article/982f9757b1bb41d3834cde83761ebc84 [Name] => EDS - DOAJ [Category] => fullText [Text] => View record in DOAJ [MouseOverText] => View record in DOAJ ) [1] => Array ( [Url] => https://resolver.ebscohost.com/openurl?custid=s6537998&groupid=main&authtype=ip,guest&sid=EBSCO:edsdoj&genre=article&issn=20726643&ISBN=&volume=13&issue=11&date=20211101&spage=4165&pages=4165-4165&title=Nutrients&atitle=Characterization%20of%20Individualized%20Glycemic%20Excursions%20during%20a%20Standardized%20Bout%20of%20Hypoglycemia-Inducing%20Exercise%20and%20Subsequent%20Hypoglycemia%20Treatment%E2%80%94A%20Pilot%20Study&id=DOI:10.3390/nu13114165 [Name] => Full Text Finder (s6537998api) [Category] => fullText [Text] => Full Text Finder [Icon] => https://imageserver.ebscohost.com/branding/images/FTF.gif [MouseOverText] => Full Text Finder ) ) |
| Items |
Array
(
[Name] => Title
[Label] => Title
[Group] => Ti
[Data] => Characterization of Individualized Glycemic Excursions during a Standardized Bout of Hypoglycemia-Inducing Exercise and Subsequent Hypoglycemia Treatment—A Pilot Study
)
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => <searchLink fieldCode="AR" term="%22Jan+Brož%22">Jan Brož</searchLink><br /><searchLink fieldCode="AR" term="%22Matthew+D%2E+Campbell%22">Matthew D. Campbell</searchLink><br /><searchLink fieldCode="AR" term="%22Jana+Urbanová%22">Jana Urbanová</searchLink><br /><searchLink fieldCode="AR" term="%22Marisa+A%2E+Nunes%22">Marisa A. Nunes</searchLink><br /><searchLink fieldCode="AR" term="%22Ludmila+Brunerová%22">Ludmila Brunerová</searchLink><br /><searchLink fieldCode="AR" term="%22Dario+Rahelić%22">Dario Rahelić</searchLink><br /><searchLink fieldCode="AR" term="%22Denisa+Janíčková+Žďárská%22">Denisa Janíčková Žďárská</searchLink><br /><searchLink fieldCode="AR" term="%22Arian+Taniwall%22">Arian Taniwall</searchLink><br /><searchLink fieldCode="AR" term="%22Marek+Brabec%22">Marek Brabec</searchLink><br /><searchLink fieldCode="AR" term="%22Vojtěch+Berka%22">Vojtěch Berka</searchLink><br /><searchLink fieldCode="AR" term="%22Juraj+Michalec%22">Juraj Michalec</searchLink><br /><searchLink fieldCode="AR" term="%22Jan+Polák%22">Jan Polák</searchLink> ) Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => Nutrients, Vol 13, Iss 11, p 4165 (2021) ) Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => MDPI AG, 2021. ) Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2021 ) Array ( [Name] => Subset [Label] => Collection [Group] => HoldingsInfo [Data] => LCC:Nutrition. Foods and food supply ) Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => <searchLink fieldCode="DE" term="%22type+1+diabetes%22">type 1 diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22exercise%22">exercise</searchLink><br /><searchLink fieldCode="DE" term="%22hypoglycemia%22">hypoglycemia</searchLink><br /><searchLink fieldCode="DE" term="%22insulin+therapy%22">insulin therapy</searchLink><br /><searchLink fieldCode="DE" term="%22glycemic+excursion%22">glycemic excursion</searchLink><br /><searchLink fieldCode="DE" term="%22hypoglycemia+treatment%22">hypoglycemia treatment</searchLink><br /><searchLink fieldCode="DE" term="%22Nutrition%2E+Foods+and+food+supply%22">Nutrition. Foods and food supply</searchLink><br /><searchLink fieldCode="DE" term="%22TX341-641%22">TX341-641</searchLink> ) Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => The glycemic response to ingested glucose for the treatment of hypoglycemia following exercise in type 1 diabetes patients has never been studied. Therefore, we aimed to characterize glucose dynamics during a standardized bout of hypoglycemia-inducing exercise and the subsequent hypoglycemia treatment with the oral ingestion of glucose. Ten male patients with type 1 diabetes performed a standardized bout of cycling exercise using an electrically braked ergometer at a target heart rate (THR) of 50% of the individual heart rate reserve, determined using the Karvonen equation. Exercise was terminated when hypoglycemia was reached, followed by immediate hypoglycemia treatment with the oral ingestion of 20 g of glucose. Arterialized blood glucose (ABG) levels were monitored at 5 min intervals during exercise and for 60 min during recovery. During exercise, ABG decreased at a mean rate of 0.11 ± 0.03 mmol/L·min−1 (minimum: 0.07, maximum: 0.17 mmol/L·min−1). During recovery, ABG increased at a mean rate of 0.13 ± 0.05 mmol/L·min−1 (minimum: 0.06, maximum: 0.19 mmol/L·min−1). Moreover, 20 g of glucose maintained recovery from hypoglycemia throughout the 60 min postexercise observation window. ) Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article ) Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => electronic resource ) Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English ) Array ( [Name] => ISSN [Label] => ISSN [Group] => ISSN [Data] => 2072-6643 ) Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => https://www.mdpi.com/2072-6643/13/11/4165; https://doaj.org/toc/2072-6643 ) Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.3390/nu13114165 ) Array ( [Name] => URL [Label] => Access URL [Group] => URL [Data] => <link linkTarget="URL" linkTerm="https://doaj.org/article/982f9757b1bb41d3834cde83761ebc84" linkWindow="_blank">https://doaj.org/article/982f9757b1bb41d3834cde83761ebc84</link> ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsdoj.982f9757b1bb41d3834cde83761ebc84 ) |
| RecordInfo |
Array
(
[BibEntity] => Array
(
[Identifiers] => Array
(
[0] => Array
(
[Type] => doi
[Value] => 10.3390/nu13114165
)
)
[Languages] => Array
(
[0] => Array
(
[Text] => English
)
)
[PhysicalDescription] => Array
(
[Pagination] => Array
(
[PageCount] => 1
[StartPage] => 4165
)
)
[Subjects] => Array
(
[0] => Array
(
[SubjectFull] => type 1 diabetes
[Type] => general
)
[1] => Array
(
[SubjectFull] => exercise
[Type] => general
)
[2] => Array
(
[SubjectFull] => hypoglycemia
[Type] => general
)
[3] => Array
(
[SubjectFull] => insulin therapy
[Type] => general
)
[4] => Array
(
[SubjectFull] => glycemic excursion
[Type] => general
)
[5] => Array
(
[SubjectFull] => hypoglycemia treatment
[Type] => general
)
[6] => Array
(
[SubjectFull] => Nutrition. Foods and food supply
[Type] => general
)
[7] => Array
(
[SubjectFull] => TX341-641
[Type] => general
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Characterization of Individualized Glycemic Excursions during a Standardized Bout of Hypoglycemia-Inducing Exercise and Subsequent Hypoglycemia Treatment—A Pilot Study
[Type] => main
)
)
)
[BibRelationships] => Array
(
[HasContributorRelationships] => Array
(
[0] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Jan Brož
)
)
)
[1] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Matthew D. Campbell
)
)
)
[2] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Jana Urbanová
)
)
)
[3] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Marisa A. Nunes
)
)
)
[4] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Ludmila Brunerová
)
)
)
[5] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Dario Rahelić
)
)
)
[6] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Denisa Janíčková Žďárská
)
)
)
[7] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Arian Taniwall
)
)
)
[8] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Marek Brabec
)
)
)
[9] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Vojtěch Berka
)
)
)
[10] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Juraj Michalec
)
)
)
[11] => Array
(
[PersonEntity] => Array
(
[Name] => Array
(
[NameFull] => Jan Polák
)
)
)
)
[IsPartOfRelationships] => Array
(
[0] => Array
(
[BibEntity] => Array
(
[Dates] => Array
(
[0] => Array
(
[D] => 01
[M] => 11
[Type] => published
[Y] => 2021
)
)
[Identifiers] => Array
(
[0] => Array
(
[Type] => issn-print
[Value] => 20726643
)
)
[Numbering] => Array
(
[0] => Array
(
[Type] => volume
[Value] => 13
)
[1] => Array
(
[Type] => issue
[Value] => 11
)
)
[Titles] => Array
(
[0] => Array
(
[TitleFull] => Nutrients
[Type] => main
)
)
)
)
)
)
)
|
| IllustrationInfo |