دورية أكاديمية
Livedoid Vasculopathy: A French Observational Study Including Therapeutic Options
| العنوان: | Livedoid Vasculopathy: A French Observational Study Including Therapeutic Options |
|---|---|
| المؤلفون: | Emma Gardette, Philippe Moguelet, Jean-David Bouaziz, Dan Lipsker, Olivier Dereure, Francois Le Pelletier, Catherine Lok, Thierry Maisonobe, Didier Bessis, Jacqueline Conard, Camille Francès, Stéphane Barete |
| المصدر: | Acta Dermato-Venereologica, Vol 98, Iss 9, Pp 842-847 (2018) |
| بيانات النشر: | Medical Journals Sweden, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | livedoidvasculopathy, peripheralneuropathy, thrombosisofdermalvessels, thrombophilia, lowmolecularweightheparin, intravenousimmunoglobulins, Dermatology, RL1-803 |
| الوصف: | Livedoid vasculopathy is a rare thrombotic cutaneous disease. This observational study aimed to assess the clinical and biological features of livedoid vasculopathy and the efficacy of treatments. Patients enrolled had typical livedoid vasculopathy both clinically and histologically. Investigation of thrombophilia was performed. Electromyography was undertaken in the presence of symptoms suggesting peripheral neuropathy. Eighteen women and 8 men were included, with a mean age of 35.5 years at onset. Twenty patients had at least one thrombophilia factor. Ten patients had a peripheral neuropathy with 2 of these patients demonstrating a specific thrombo-occlusive vasculopathy on muscle biopsy. Anticoagulation with low molecular weight heparin was the most prescribed therapy and was associated with the best outcome (effective in 14 patients). Eight patients had severe disease refractory to anticoagulation and required intravenous immunoglobulins, producing a good response in 6 patients. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0001-5555 1651-2057 00015555 |
| العلاقة: | https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2965Test; https://doaj.org/toc/0001-5555Test; https://doaj.org/toc/1651-2057Test |
| DOI: | 10.2340/00015555-2965 |
| الوصول الحر: | https://doaj.org/article/68afb24ddfa7468c9a84cdebe9aada06Test |
| رقم الانضمام: | edsdoj.68afb24ddfa7468c9a84cdebe9aada06 |
| قاعدة البيانات: | Directory of Open Access Journals |
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