دورية أكاديمية
Onco-Preventive and Chemo-Protective Effects of Apple Bioactive Compounds
العنوان: | Onco-Preventive and Chemo-Protective Effects of Apple Bioactive Compounds |
---|---|
المؤلفون: | Linda Nezbedova, Tony McGhie, Mark Christensen, Julian Heyes, Noha Ahmed Nasef, Sunali Mehta |
المصدر: | Nutrients, Vol 13, Iss 11, p 4025 (2021) |
بيانات النشر: | MDPI AG, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Nutrition. Foods and food supply |
مصطلحات موضوعية: | fruit, apple, phytochemicals, cancer, chemoprevention, antioxidants, Nutrition. Foods and food supply, TX341-641 |
الوصف: | Cancer is one of the leading causes of death globally. Epidemiological studies have strongly linked a diet high in fruits to a lower incidence of cancer. Furthermore, extensive research shows that secondary plant metabolites known as phytochemicals, which are commonly found in fruits, have onco-preventive and chemo-protective effects. Apple is a commonly consumed fruit worldwide that is available all year round and is a rich source of phytochemicals. In this review, we summarize the association of apple consumption with cancer incidence based on findings from epidemiological and cohort studies. We further provide a comprehensive review of the main phytochemical patterns observed in apples and their bioavailability after consumption. Finally, we report on the latest findings from in vitro and in vivo studies highlighting some of the key molecular mechanisms targeted by apple phytochemicals in relation to inhibiting multiple ‘hallmarks of cancer’ that are important in the progression of cancer. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2072-6643 |
العلاقة: | https://www.mdpi.com/2072-6643/13/11/4025Test; https://doaj.org/toc/2072-6643Test |
DOI: | 10.3390/nu13114025 |
الوصول الحر: | https://doaj.org/article/c6361153d4a545eea4fb2e157105abd9Test |
رقم الانضمام: | edsdoj.6361153d4a545eea4fb2e157105abd9 |
قاعدة البيانات: | Directory of Open Access Journals |
كن أول من يترك تعليقا!