دورية أكاديمية
Identification of perineural invasion at imaging staging as a novel potential risk factor in rectal cancer: A case report
العنوان: | Identification of perineural invasion at imaging staging as a novel potential risk factor in rectal cancer: A case report |
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المؤلفون: | Sara Del Tufo, Umberto Atripaldi, Antonella Nicastro, Iacopo Panarese, Davide Ciardiello, Valerio Nardone, Francesco Selvaggi, Roberto Grassi, Salvatore Cappabianca, Erika Martinelli, Alfonso Reginelli |
المصدر: | Radiology Case Reports, Vol 19, Iss 9, Pp 3626-3630 (2024) |
بيانات النشر: | Elsevier, 2024. |
سنة النشر: | 2024 |
المجموعة: | LCC:Medical physics. Medical radiology. Nuclear medicine |
مصطلحات موضوعية: | Rectal cancer, Biomarkers, Perineural invasion, MRI, Staging, Medical physics. Medical radiology. Nuclear medicine, R895-920 |
الوصف: | Treatment of rectal cancer has improved over the years thanks to a multidisciplinary approach. A correct staging has a fundamental role for risk stratification and to define the best treatment for each patient. Unfortunately, approximately 30% of patients with locally advanced rectal cancers will experience tumor recurrence. Thus, the identification of novel clinical-pathological and radiological prognostic factors represents an urgent unmet clinical need. Here we report the case of a patient with radically resected localized rectal cancer who developed an impressive early pelvic recurrence. To better understand the clinical scenario, we have studied the possible factors related to the aggressiveness of the disease. The only poor prognosticfactor that was evidenced at histological report was perineural invasion. Therefore, we questioned whether we could evaluate perineural invasion with imaging, similar to head and neck tumors. Learning from this clinical case, we believe that improving the risk stratification and radiology reporting is necessary to provide the best care for the patient and allow for a better prognosis prediction. Of course, our data should be considered as hypothesis generating and should be further investigated and validated in larger and prospective studies. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1930-0433 |
العلاقة: | http://www.sciencedirect.com/science/article/pii/S193004332400428XTest; https://doaj.org/toc/1930-0433Test |
DOI: | 10.1016/j.radcr.2024.05.031 |
الوصول الحر: | https://doaj.org/article/eec5cbb29fdd4342a5a6cb660c4ec7b4Test |
رقم الانضمام: | edsdoj.5cbb29fdd4342a5a6cb660c4ec7b4 |
قاعدة البيانات: | Directory of Open Access Journals |