دورية أكاديمية
The Signaling Network Controlling C. elegans Vulval Cell Fate Patterning
العنوان: | The Signaling Network Controlling C. elegans Vulval Cell Fate Patterning |
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المؤلفون: | Hanna Shin, David J. Reiner |
المصدر: | Journal of Developmental Biology, Vol 6, Iss 4, p 30 (2018) |
بيانات النشر: | MDPI AG, 2018. |
سنة النشر: | 2018 |
المجموعة: | LCC:Biology (General) |
مصطلحات موضوعية: | EGF, EGFR, Ras, Notch, DSL, Raf, RalGEF, Ral, signal transduction, MAP kinase, Biology (General), QH301-705.5 |
الوصف: | EGF, emitted by the Anchor Cell, patterns six equipotent C. elegans vulval precursor cells to assume a precise array of three cell fates with high fidelity. A group of core and modulatory signaling cascades forms a signaling network that demonstrates plasticity during the transition from naïve to terminally differentiated cells. In this review, we summarize the history of classical developmental manipulations and molecular genetics experiments that led to our understanding of the signals governing this process, and discuss principles of signal transduction and developmental biology that have emerged from these studies. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2221-3759 |
العلاقة: | https://www.mdpi.com/2221-3759/6/4/30Test; https://doaj.org/toc/2221-3759Test |
DOI: | 10.3390/jdb6040030 |
الوصول الحر: | https://doaj.org/article/4295b65ff4a54da78991df7d347fbb00Test |
رقم الانضمام: | edsdoj.4295b65ff4a54da78991df7d347fbb00 |
قاعدة البيانات: | Directory of Open Access Journals |