دورية أكاديمية
Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia
العنوان: | Genetic hierarchy and temporal variegation in the clonal history of acute myeloid leukaemia |
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المؤلفون: | Pierre Hirsch, Yanyan Zhang, Ruoping Tang, Virginie Joulin, Hélène Boutroux, Elodie Pronier, Hannah Moatti, Pascale Flandrin, Christophe Marzac, Dominique Bories, Fanny Fava, Hayat Mokrani, Aline Betems, Florence Lorre, Rémi Favier, Frédéric Féger, Mohamad Mohty, Luc Douay, Ollivier Legrand, Chrystèle Bilhou-Nabera, Fawzia Louache, François Delhommeau |
المصدر: | Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016) |
بيانات النشر: | Nature Portfolio, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Science |
مصطلحات موضوعية: | Science |
الوصف: | Pre-leukaemic clones, together with the propensity to cause disease in mice, are characterized by appearing early in myeloid leukaemia and being found at relapse. Here, the authors identify clones in human samples and find that they are characterized by hierarchically organized genetic lesions, which can be used to track evolution of the disease. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2041-1723 |
العلاقة: | https://doaj.org/toc/2041-1723Test |
DOI: | 10.1038/ncomms12475 |
الوصول الحر: | https://doaj.org/article/2dbbe918315649bd816bccb6c1b9c78cTest |
رقم الانضمام: | edsdoj.2dbbe918315649bd816bccb6c1b9c78c |
قاعدة البيانات: | Directory of Open Access Journals |