دورية أكاديمية
Semi-stable production of bovine IL-4 and GM-CSF in the mammalian episomal expression system
العنوان: | Semi-stable production of bovine IL-4 and GM-CSF in the mammalian episomal expression system |
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المؤلفون: | Blanco Federico Carlos, Vazquez Cristina Lourdes, García Julia Sabio y, Rocha Rosana Valeria, Gravisaco María José, Forrellad Marina Andrea, Magistrelli Giovanni, Bigi Fabiana |
المصدر: | Journal of Veterinary Research, Vol 65, Iss 3, Pp 315-321 (2021) |
بيانات النشر: | Sciendo, 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Veterinary medicine |
مصطلحات موضوعية: | bovine gm-csf, bovine il-4, dendritic cells, macrophages, mammalian episomal expression, Veterinary medicine, SF600-1100 |
الوصف: | Granulocyte-macrophage colony stimulating factor (GM-CSF) and interleukin-4 (IL-4) are cytokines widely used in ex vivo monocyte differentiation experiments, vaccine formulations and disease treatment. The aim of this study was to produce recombinant bovine GM-CSF and IL-4 in an episomal expression system that conserves the postransductional modification of the native proteins and to use the products to differentiate bovine monocytes into dendritic cells. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2450-8608 2021-0043 |
العلاقة: | https://doaj.org/toc/2450-8608Test |
DOI: | 10.2478/jvetres-2021-0043 |
الوصول الحر: | https://doaj.org/article/239419e86afa4b7bb6a838e9e1f988e6Test |
رقم الانضمام: | edsdoj.239419e86afa4b7bb6a838e9e1f988e6 |
قاعدة البيانات: | Directory of Open Access Journals |