دورية أكاديمية
Synacthen Stimulation Test Following Unilateral Adrenalectomy Needs to Be Interpreted With Caution
العنوان: | Synacthen Stimulation Test Following Unilateral Adrenalectomy Needs to Be Interpreted With Caution |
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المؤلفون: | Shamaila Zaman, Raya Almazrouei, Amir H. Sam, Aimee N. DiMarco, Jeannie F. Todd, Fausto F. Palazzo, Tricia Tan, Waljit S. Dhillo, Karim Meeran, Florian Wernig |
المصدر: | Frontiers in Endocrinology, Vol 12 (2021) |
بيانات النشر: | Frontiers Media S.A., 2021. |
سنة النشر: | 2021 |
المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
مصطلحات موضوعية: | adrenalectomy, synacthen stimulation test, adrenal insufficiency, over-night dexamethasone suppression test, autonomous cortisol secretion, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
الوصف: | BackgroundCortisol levels in response to stress are highly variable. Baseline and stimulated cortisol levels are commonly used to determine adrenal function following unilateral adrenalectomy. We report the results of synacthen stimulation testing following unilateral adrenalectomy in a tertiary referral center.MethodsData were collected retrospectively for 36 patients who underwent synacthen stimulation testing one day post unilateral adrenalectomy. None of the patients had clinical signs of hypercortisolism preoperatively. No patient received pre- or intraoperative steroids. Patients with overt Cushing’s syndrome were excluded.ResultsThe median age was 58 (31-79) years. Preoperatively, 16 (44%) patients had a diagnosis of pheochromocytoma, 12 (33%) patients had primary aldosteronism and 8 (22%) patients had non-functioning adenomas with indeterminate/atypical imaging characteristics necessitating surgery. Preoperative overnight dexamethasone suppression test results revealed that 6 of 29 patients failed to suppress cortisol to |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1664-2392 |
العلاقة: | https://www.frontiersin.org/articles/10.3389/fendo.2021.654600/fullTest; https://doaj.org/toc/1664-2392Test |
DOI: | 10.3389/fendo.2021.654600 |
الوصول الحر: | https://doaj.org/article/0f58c973711e446997f340718b6e521eTest |
رقم الانضمام: | edsdoj.0f58c973711e446997f340718b6e521e |
قاعدة البيانات: | Directory of Open Access Journals |