دورية
Simple and sensitive LC-UV method for simultaneous analysis of hydrochlorothiazide and candesartan cilexetil in pharmaceutical formulations
العنوان: | Simple and sensitive LC-UV method for simultaneous analysis of hydrochlorothiazide and candesartan cilexetil in pharmaceutical formulations |
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المؤلفون: | Qutab, S. S., Razzaq, S. N., Ashfaq, M., Shuja, Z. A., Khan, I. U. |
المصدر: | Acta Chromatographica. |
الوصف: | A simple, sensitive, and inexpensive high-performance liquid-chromatographic method has been developed for simultaneous determination of hydrochlorothiazide and candesartan cilexetil in pharmaceutical formulations. Chromatographic separation was achieved on a Phenyl-2 column with a 25:75:0.2 mixture of 0.02 M potassium dihydrogen phosphate, methanol, and triethylamine, final pH 6.0 š 0.1, as mobile phase. Detection was at 271 nm. Response was a linear function of concentration in the range 5–45 µg mL-1 for hydrochlorothiazide and 12–56 µg mL-1 for candesartan cilexetil; the correlation coefficients were 0.9993 and 0.9991, respectively. Total elution time for the two components was less than 5 min. |
نوع الوثيقة: | Article |
اللغة: | English |
الوصول الحر: | http://yadda.icm.edu.pl/baztech/element/bwmeta1.element.baztech-article-BATA-0003-0010Test |
رقم الانضمام: | edsbzt.bwmeta1.element.baztech.article.BATA.0003.0010 |
قاعدة البيانات: | BazTech |
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