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Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003–2013 ; Emerg Infect Dis

التفاصيل البيبلوغرافية
العنوان: Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003–2013 ; Emerg Infect Dis
المساهمون: von Mollendorf, Claire, Cohen, Cheryl, Tempia, Stefano, Meiring, Susan, de Gouveia, Linda, Quan, Vanessa, Lengana, Sarona, Karstaedt, Alan, Dawood, Halima, Seetharam, Sharona, Lekalakala, Ruth, Madhi, Shabir A., Klugman, Keith P., von Gottberg, Anne, for the Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa (GERMS-SA)
المصدر: Emerg Infect Dis. 22(2):261-270.
المجموعة: CDC Stacks (Centers for Disease Control and Prevention)
مصطلحات موضوعية: Research, Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003–2013, Streptococcus pneumoniae, serotype 1, pneumococcal conjugate vaccine, PCV13, epidemiology, surveillance, invasive, vaccination, incidence, pneumonia, bacteremia, immunization, streptococci, Adolescent, Adult, Aged, Child, Preschool, History, Hospitalization, Humans, Infant, Newborn, Middle Aged, Mortality
الوقت: 21st Century
الوصف: In South Africa, 7-valent pneumococcal conjugate vaccine (PCV) was introduced in April 2009 and replaced with 13-valent PCV in April 2011. We describe the epidemiology of serotype 1 Streptococcus pneumoniae disease during the pre- and post-PCV eras (2003-2013). Using laboratory-based invasive pneumococcal disease (IPD) surveillance, we calculated annual incidences, identified IPD clusters, and determined serotype 1-associated factors. Of 46,483 IPD cases, 4,544 (10%) were caused by serotype 1. Two clusters of serotype 1 infection were detected during 2003-2004 and 2008-2012, but incidence decreased after 2011. Among children <5 years of age, those who had non-serotype 1 IPD had shorter hospital stays, fewer cases of penicillin-nonsusceptible disease, and lower HIV prevalence and in-hospital death rates than did those with serotype 1 IPD; similar factors were noted for older patients. Serotype 1 IPD had distinctive clinical features in South Africa, and annual incidences fluctuated, with decreases noted after the introduction of PCV13. ; U2G PS001328/PS/NCHHSTP CDC HHS/United States ; 5U2GPS001328/PHS HHS/United States ; 26812214 ; PMC4734528
نوع الوثيقة: other/unknown material
اللغة: unknown
العلاقة: cdc:37990; http://stacks.cdc.gov/view/cdc/37990Test/
الإتاحة: http://stacks.cdc.gov/view/cdc/37990Test/
رقم الانضمام: edsbas.ED0C28D9
قاعدة البيانات: BASE
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