دورية أكاديمية
Autophagy in major human diseases.
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edsbas BASE edsbas.EBE211FE 927 3 Academic Journal academicJournal 926.820373535156 |
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Pharmacological and genetic interventions impairing autophagy responses promote or aggravate disease in a plethora of experimental models. Consistently, mutations in autophagy-related processes cause severe human pathologies. Here, we review and discuss preclinical data linking autophagy dysfunction to the pathogenesis of major human disorders including cancer as well as cardiovascular, neurodegenerative, metabolic, pulmonary, renal, infectious, musculoskeletal, and ocular disorders. ) Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article in journal/newspaper ) Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => unknown ) Array ( [Name] => NoteTitleSource [Label] => Relation [Group] => SrcInfo [Data] => https://figshare.com/articles/journal_contribution/Autophagy_in_major_human_diseases_/16775662 ) Array ( [Name] => DOI [Label] => DOI [Group] => ID [Data] => 10.25418/crick.16775662.v1 ) Array ( [Name] => URL [Label] => Availability [Group] => URL [Data] => https://doi.org/10.25418/crick.16775662.v1 ) Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => CC BY 4.0 ) Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsbas.EBE211FE ) |
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