مراجعة

Diagnosis of pleuroparenchymal fibroelastosis: a review

التفاصيل البيبلوغرافية
العنوان: Diagnosis of pleuroparenchymal fibroelastosis: a review
المؤلفون: Tetikkurt, C., Ozturk, B.C., Gungordu, N.
بيانات النشر: Page Press Publications
سنة النشر: 2023
مصطلحات موضوعية: interstitial lung disease, pleural fibrosis, pleuroparenchymal fibroelastosis, PPFE, pulmonary fibrosis, C reactive protein, collagen, elastin, methylprednisolone, adult, arterial carbon dioxide tension, arterial oxygen tension, body weight loss, bronchiectasis, case report, clinical article, clinical feature, corticosteroid therapy, crackle, current smoker, differential diagnosis, dry cough, elastosis, electrocardiogram, exertional dyspnea, female, fibrosing alveolitis, forced expiratory volume, forced vital capacity, ground glass opacity
الوصف: Pleuroparenchymal fibroelastosis (PPFE) is a rare lung disease with unprecedented features characterized by fibroelastotic changes in the subpleural lung parenchyma affecting the upper lobes. PPFE is usually idiopathic, but it can be caused by infection, autoimmunity, bone marrow or lung transplantation, or a genetic predisposition. Histopathologic examination of lung biopsy samples reveals homogenous subpleural fibrosis and abundant elastic fibers, allowing for a definitive diagnosis. As PPFE mimics many interstitial lung diseases, clinicians face significant difficulties in making a definitive final diagnosis. Since most disease-related comorbid conditions manifest at an advanced stage, invasive tissue sampling for histopathologic evaluation is consistently impossible. Such a patient presentation highlights the importance of an analysis based solely on clinical findings, which would provide a definitive diagnosis without the need for a biopsy. Because of its exceptional and inconceivable presentation, PPFE creates a diagnostic dilemma. In light of our two cases and the literature data, we present a diagnostic assessment score assay that relies solely on clinical manifestations without histopathological tissue verification to shed light on the diagnosis of PPFE. This review focuses on PPFE identification through the use of a diagnostic assessment analysis to improve early disease recognition without the use of invasive diagnostic interventions to obtain biopsy samples for histopathologic evaluation. This analytic approach, while not diagnostic in and of itself, may provide a useful pathway for differential diagnosis and may preclude redundant initiatives. ©Copyright: the Author(s) 2022.
نوع الوثيقة: review
اللغة: English
تدمد: 11220643
العلاقة: Monaldi Archives for Chest Disease; Diğer; https://doi.org/10.4081/monaldi.2022.2363Test; https://hdl.handle.net/20.500.12831/17970Test; 93; 67; 74; 2-s2.0-85164209781
DOI: 10.4081/monaldi.2022.2363
الإتاحة: https://doi.org/10.4081/monaldi.2022.2363Test
https://doi.org/20.500.12831/17970Test
https://hdl.handle.net/20.500.12831/17970Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.E8BCB9E7
قاعدة البيانات: BASE
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