دورية أكاديمية
أعرض في EDS

Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats

التفاصيل البيبلوغرافية
العنوان: Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats
المؤلفون: Wu,Hui, Chang,Weiyu, Deng,Yanglin, Chen,Xinli, Ding,Yongli, Li,Xuesong, Dong,Liang
المصدر: Brazilian Journal of Cardiovascular Surgery v.34 n.6 2019
بيانات النشر: Sociedade Brasileira de Cirurgia Cardiovascular
سنة النشر: 2019
المجموعة: SciELO Brazil (Scientific Electronic Library Online)
مصطلحات موضوعية: Hemodynamics, Myocardial Reperfusion Injury, Creatine Kinase, Troponin I, L-Lactate Dehydrogenase, Disease Outbreaks, Animal, Rats
الوصف: Objective: To study the response of myocardial ischemia/reperfusion injury (MI/RI) in rats to simulated geomagnetic activity. Methods: In a simulated strong geomagnetic outbreak, the MI/RI rat models were radiated, and their area of myocardial infarction, hemodynamic parameters, creatine kinase (CK), lactate dehydrogenase (LDH), melatonin, and troponin I values were measured after a 24-hour intervention. Results: Our analysis indicates that the concentrations of troponin I in the geomagnetic shielding+operation group were lower than in the radiation+operation group (P<0.05), the concentrations of melatonin in the shielding+operation group and normal+operation group were higher than in the radiation + operation group (P<0.01), and the concentrations of CK in the shielding + operation group were lower than in the radiation + operation group and normal + operation group (P<0.05). Left ventricular developed pressure (LVDP) and ± dP/dtmax in the radiation+operation group were lower than in the shielding + operation group and normal+operation group (P<0.01). Left ventricular end-diastolic pressure (LEVDP) in the shielding + operation group was higher than in the normal + operation group (P<0.05). There was no significant difference in area of myocardial infarction and LDH between the shielding + operation group and the radiation + operation group. Conclusion: Our data suggest that geomagnetic activity is important in regulating myocardial reperfusion injury. The geomagnetic shielding has a protective effect on myocardial injury, and the geomagnetic radiation is a risk factor for aggravating the cardiovascular and cerebrovascular diseases.
نوع الوثيقة: article in journal/newspaper
وصف الملف: text/html
اللغة: English
الإتاحة: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000600006Test
حقوق: info:eu-repo/semantics/openAccess
رقم الانضمام: edsbas.E6CAF309
قاعدة البيانات: BASE
ResultId 1
Header edsbas
BASE
edsbas.E6CAF309
904
3
Academic Journal
academicJournal
903.687927246094
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&scope=site&db=edsbas&AN=edsbas.E6CAF309&custid=s6537998&authtype=sso
FullText Array ( [Availability] => 0 )
Array ( [0] => Array ( [Url] => http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-76382019000600006# [Name] => EDS - BASE [Category] => fullText [Text] => View record in BASE [MouseOverText] => View record in BASE ) )
Items Array ( [Name] => Title [Label] => Title [Group] => Ti [Data] => Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats )
Array ( [Name] => Author [Label] => Authors [Group] => Au [Data] => &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Wu%2CHui%22&quot;&gt;Wu,Hui&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chang%2CWeiyu%22&quot;&gt;Chang,Weiyu&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Deng%2CYanglin%22&quot;&gt;Deng,Yanglin&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Chen%2CXinli%22&quot;&gt;Chen,Xinli&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Ding%2CYongli%22&quot;&gt;Ding,Yongli&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Li%2CXuesong%22&quot;&gt;Li,Xuesong&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Dong%2CLiang%22&quot;&gt;Dong,Liang&lt;/searchLink&gt; )
Array ( [Name] => TitleSource [Label] => Source [Group] => Src [Data] => Brazilian Journal of Cardiovascular Surgery v.34 n.6 2019 )
Array ( [Name] => Publisher [Label] => Publisher Information [Group] => PubInfo [Data] => Sociedade Brasileira de Cirurgia Cardiovascular )
Array ( [Name] => DatePubCY [Label] => Publication Year [Group] => Date [Data] => 2019 )
Array ( [Name] => Subset [Label] => Collection [Group] => HoldingsInfo [Data] => SciELO Brazil (Scientific Electronic Library Online) )
Array ( [Name] => Subject [Label] => Subject Terms [Group] => Su [Data] => &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hemodynamics%22&quot;&gt;Hemodynamics&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Myocardial+Reperfusion+Injury%22&quot;&gt;Myocardial Reperfusion Injury&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Creatine+Kinase%22&quot;&gt;Creatine Kinase&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Troponin+I%22&quot;&gt;Troponin I&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22L-Lactate+Dehydrogenase%22&quot;&gt;L-Lactate Dehydrogenase&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Disease+Outbreaks%22&quot;&gt;Disease Outbreaks&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Animal%22&quot;&gt;Animal&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Rats%22&quot;&gt;Rats&lt;/searchLink&gt; )
Array ( [Name] => Abstract [Label] => Description [Group] => Ab [Data] => Objective: To study the response of myocardial ischemia/reperfusion injury (MI/RI) in rats to simulated geomagnetic activity. Methods: In a simulated strong geomagnetic outbreak, the MI/RI rat models were radiated, and their area of myocardial infarction, hemodynamic parameters, creatine kinase (CK), lactate dehydrogenase (LDH), melatonin, and troponin I values were measured after a 24-hour intervention. Results: Our analysis indicates that the concentrations of troponin I in the geomagnetic shielding+operation group were lower than in the radiation+operation group (P&lt;0.05), the concentrations of melatonin in the shielding+operation group and normal+operation group were higher than in the radiation + operation group (P&lt;0.01), and the concentrations of CK in the shielding + operation group were lower than in the radiation + operation group and normal + operation group (P&lt;0.05). Left ventricular developed pressure (LVDP) and &#177; dP/dtmax in the radiation+operation group were lower than in the shielding + operation group and normal+operation group (P&lt;0.01). Left ventricular end-diastolic pressure (LEVDP) in the shielding + operation group was higher than in the normal + operation group (P&lt;0.05). There was no significant difference in area of myocardial infarction and LDH between the shielding + operation group and the radiation + operation group. Conclusion: Our data suggest that geomagnetic activity is important in regulating myocardial reperfusion injury. The geomagnetic shielding has a protective effect on myocardial injury, and the geomagnetic radiation is a risk factor for aggravating the cardiovascular and cerebrovascular diseases. )
Array ( [Name] => TypeDocument [Label] => Document Type [Group] => TypDoc [Data] => article in journal/newspaper )
Array ( [Name] => Format [Label] => File Description [Group] => SrcInfo [Data] => text/html )
Array ( [Name] => Language [Label] => Language [Group] => Lang [Data] => English )
Array ( [Name] => URL [Label] => Availability [Group] => URL [Data] => http://www.scielo.br/scielo.php?script=sci_arttext&amp;pid=S0102-76382019000600006 )
Array ( [Name] => Copyright [Label] => Rights [Group] => Cpyrght [Data] => info:eu-repo/semantics/openAccess )
Array ( [Name] => AN [Label] => Accession Number [Group] => ID [Data] => edsbas.E6CAF309 )
RecordInfo Array ( [BibEntity] => Array ( [Languages] => Array ( [0] => Array ( [Text] => English ) ) [Subjects] => Array ( [0] => Array ( [SubjectFull] => Hemodynamics [Type] => general ) [1] => Array ( [SubjectFull] => Myocardial Reperfusion Injury [Type] => general ) [2] => Array ( [SubjectFull] => Creatine Kinase [Type] => general ) [3] => Array ( [SubjectFull] => Troponin I [Type] => general ) [4] => Array ( [SubjectFull] => L-Lactate Dehydrogenase [Type] => general ) [5] => Array ( [SubjectFull] => Disease Outbreaks [Type] => general ) [6] => Array ( [SubjectFull] => Animal [Type] => general ) [7] => Array ( [SubjectFull] => Rats [Type] => general ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Effect of Simulated Geomagnetic Activity on Myocardial Ischemia/Reperfusion Injury in Rats [Type] => main ) ) ) [BibRelationships] => Array ( [HasContributorRelationships] => Array ( [0] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Wu,Hui ) ) ) [1] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Chang,Weiyu ) ) ) [2] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Deng,Yanglin ) ) ) [3] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Chen,Xinli ) ) ) [4] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Ding,Yongli ) ) ) [5] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Li,Xuesong ) ) ) [6] => Array ( [PersonEntity] => Array ( [Name] => Array ( [NameFull] => Dong,Liang ) ) ) ) [IsPartOfRelationships] => Array ( [0] => Array ( [BibEntity] => Array ( [Dates] => Array ( [0] => Array ( [D] => 01 [M] => 01 [Type] => published [Y] => 2019 ) ) [Identifiers] => Array ( [0] => Array ( [Type] => issn-locals [Value] => edsbas ) [1] => Array ( [Type] => issn-locals [Value] => edsbas.oa ) ) [Titles] => Array ( [0] => Array ( [TitleFull] => Brazilian Journal of Cardiovascular Surgery v.34 n.6 2019 [Type] => main ) ) ) ) ) ) )
IllustrationInfo