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Prevalence and risk factors of diabetic retinopathy in migrant Indians in an urbanized society in Asia: The Singapore Indian eye study

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العنوان: Prevalence and risk factors of diabetic retinopathy in migrant Indians in an urbanized society in Asia: The Singapore Indian eye study
المؤلفون: Wu, R, Wong, TY, Cheung, N, Mitchell, P, Wang, JJ, Ikram, MK, Lavanya, R, Zheng, Y, Lamoureux, EL, Saw, SM, Aung, T
بيانات النشر: //www.elsevier.com/locate/ophtha
United States
سنة النشر: 2012
المجموعة: University of Hong Kong: HKU Scholars Hub
مصطلحات موضوعية: Urban Population - Statistics & Numerical Data, Prevalence, Middle Aged, Male, India - Ethnology, Humans, Hemoglobin A, Glycosylated - Metabolism, Female, Diabetic Retinopathy - Diagnosis - Ethnology, Diabetes Mellitus, Type 2 - Ethnology, Type 1 - Ethnology, Transients And Migrants - Statistics & Numerical Data, Time Factors, Singapore - Epidemiology, Risk Factors, Questionnaires, Blood Pressure, Aged, 80 And Over, Adult
الوصف: Purpose: To describe the prevalence of and risk factors for diabetic retinopathy (DR) in Indian persons living in a newly urbanized society in Asia. Design: Population-based study. Participants: Ethnic Indians aged <40 years living in Singapore. Methods: The Singapore Indian Eye Study was conducted between 2007 and 2009. All participants underwent an extensive ophthalmic examination, including retinal photographs obtained after pupil dilation. These images were graded for the presence and severity of DR using the modified Airlie House classification system. Diabetes was defined as hemoglobin A1c level of <6.5%, use of diabetic medication, or a physician diagnosis of diabetes. Risk factors were measured using questionnaires, clinical assessments, or laboratory tests. Main Outcome Measures: Any DR, diabetic macular edema (DME), or vision-threatening DR (VTDR). Results: Among the 3400 participants, the age-standardized prevalence was 33.6% (95% confidence interval [CI], 31.4-35.8) for diabetes and 10.5% (95% CI, 9.3-11.8) for DR. Among those with diabetes only, the age-standardized prevalence was 30.4% (95% CI, 26.5-34.8) for any DR, 7.2% (95% CI, 5.3-9.7) for DME, and 7.1% (95% CI, 5.4-9.5) for VTDR. In multivariate analysis, independent risk factors for any DR were younger age (odds ratio [OR], 0.98; 95% CI, 0.96-1.00, per year increase), longer diabetes duration (OR, 1.09; 95% CI, 1.07-1.11 per year increase), higher hemoglobin A1c (OR, 1.23; 95% CI, 1.13-1.34 per percent increase), higher systolic blood pressure (OR, 1.01; 95% CI, 1.00-1.02 per 1-mmHg increase), lower diastolic blood pressure (OR, 0.97; 95% CI, 0.96-0.99 per 1-mmHg increase), history of previous stroke (OR, 2.16; 95% CI, 1.12-4.16), and insulin treatment (OR, 2.99; 95% CI, 1.84-4.87). Similar independent risk factors, except for blood pressure, were found for VTDR. Additionally, persons with lower income and living in smaller houses were associated with VTDR. Conclusions: One in 3 migrant Indians living in newly urbanized Asian societies ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 0161-6420
العلاقة: Ophthalmology; http://www.scopus.com/mlt/select.url?eid=2-s2.0-84867097509&selection=ref&src=s&origin=recordpageTest; Ophthalmology, 2012, v. 119 n. 10, p. 2119-2124; 2124; WOS:000310581900027; 10; eid_2-s2.0-84867097509; 2119; http://hdl.handle.net/10722/183623Test; 119
DOI: 10.1016/j.ophtha.2012.04.027
الإتاحة: https://doi.org/10.1016/j.ophtha.2012.04.027Test
http://hdl.handle.net/10722/183623Test
رقم الانضمام: edsbas.C8C9B56B
قاعدة البيانات: BASE
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