دورية أكاديمية

Y-Chromosome Haplogroups in the Bosnian-Herzegovinian Population Based on 23 Y-STR Loci

التفاصيل البيبلوغرافية
العنوان: Y-Chromosome Haplogroups in the Bosnian-Herzegovinian Population Based on 23 Y-STR Loci
المؤلفون: Serkan Doğan, Adna Ašić, Gulsen Doğan, Larisa Besic, Damir Marjanovic
المساهمون: Serkan Doğan, Adna Ašić, Gulsen Doğan, Larisa Besic, Damir Marjanovic
المصدر: https://doi.org/10.13110/humanbiology.88.3.0201Test.
بيانات النشر: Wayne State University Press
سنة النشر: 2016
المجموعة: BioOne Online Journals
جغرافية الموضوع: world
الوصف: In a study of the Bosnian-Herzegovinian (B&H) population, Y-chromosome marker frequencies for 100 individuals, generated using the PowerPlex Y23 kit, were used to perform Y-chromosome haplogroup assignment via Whit Athey's Haplogroup Predictor. This algorithm determines Y-chromosome haplogroups from Y-chromosome short tandem repeat (Y-STR) data using a Bayesian probability-based approach. The most frequent haplogroup appeared to be I2a, with a prevalence of 49%, followed by R1a and E1b1b, each accounting for 17% of all haplogroups within the population. Remaining haplogroups were J2a (5%), I1 (4%), R1b (4%), J2b (2%), G2a (1%), and N (1%). These results confirm previously published preliminary B&H population data published over 10 years ago, especially the prediction about the B&H population being a part of the Western Balkan area, which served as the Last Glacial Maximum refuge for the Paleolithic human European population. Furthermore, the results corroborate the hypothesis that this area was a significant stopping point on the “Middle East—Europe highway” during the Neolithic farmer migrations. Finally, since these results are almost completely in accordance with previously published data on B&H and neighboring populations generated by Y-chromosome single nucleotide polymorphism analysis, it can be concluded that in silico analysis of Y-STRs is a reliable method for approximation of the Y-chromosome haplogroup diversity of an examined population.
نوع الوثيقة: text
وصف الملف: text/HTML
اللغة: English
DOI: 10.13110/humanbiology.88.3.0201
الإتاحة: https://doi.org/10.13110/humanbiology.88.3.0201Test
حقوق: All rights reserved.
رقم الانضمام: edsbas.C329D971
قاعدة البيانات: BASE
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