دورية أكاديمية
Development and validation of a scoring system to predict esophagogastroduodenoscopy necessity
العنوان: | Development and validation of a scoring system to predict esophagogastroduodenoscopy necessity |
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المؤلفون: | Yang, Jing, Yan, Jing Shuang, Xiong, Cen Xi, Zhang, Xiao Mei, Shen, Lei, Zhi, Jun Li, Ma, Shu Yun, Dong, Hong Xia, Yang, Yun Sheng |
المصدر: | Journal of Digestive Diseases ; volume 24, issue 12, page 671-680 ; ISSN 1751-2972 1751-2980 |
بيانات النشر: | Wiley |
سنة النشر: | 2023 |
المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
الوصف: | Objective This study aimed to develop and validate a scoring system for predicting the need for esophagogastroduodenoscopy (EGD) in clinical practice to enhance accuracy and reduce misapplications. Methods From February 2021 to April 2022, outpatients scheduled for EGD at the Department of Gastroenterology in our hospital were recruited. Patients completed the system evaluation by providing clinical symptoms, relevant medical history, and endoscopic findings. Patients were randomly divided into the training and validation cohorts (at 2:1 ratio). The optimal algorithm was selected from five alternatives including a parallel test. Six physicians participated in a human‐computer comparative validation. Sensitivity and negative likelihood ratio (−LR) were used as the primary indicators. Results Altogether 865 patients were enrolled, with 578 in the training cohort and 287 in the validation cohort. The scoring system comprised 21 variables, including age, 13 typical clinical symptoms, and seven medical history variables. The parallel test was selected as the final algorithm. Positive EGD findings were reported in 54.5% of the training cohort and 62.7% of the validation cohort. The scoring system demonstrated a sensitivity of 79.0% in the training cohort and 83.9% in the validation cohort, with −LR being 0.627 and 0.615, respectively. Compared to physicians, the scoring system exhibited higher sensitivity (84.0% vs 68.7%, P = 0.02) and a lower −LR (1.11 vs 2.41, P = 0.439). Conclusions We developed a scoring system to predict the necessity of EGD using a parallel test algorithm, which was user‐friendly and effective, as evidenced by single‐center validation. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
DOI: | 10.1111/1751-2980.13241 |
الإتاحة: | https://doi.org/10.1111/1751-2980.13241Test |
حقوق: | http://creativecommons.org/licenses/by-nc-nd/4.0Test/ |
رقم الانضمام: | edsbas.AD58DCFF |
قاعدة البيانات: | BASE |